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Treponema Pallidum (Syphilis) Screening Cascade Blood Test

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The Treponema Pallidum (Syphilis) Screening Cascade Blood Test checks for syphilis, a serious infection, by looking for specific germs in your blood, helping to catch it early so you can get treated and stay healthy.

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What is the purpose of this test?

The Treponema Pallidum (Syphilis) Screening Cascade Blood Test is designed to detect the presence of syphilis, a sexually transmitted infection caused by the bacteria Treponema pallidum. This test is important because syphilis can cause serious health problems if left untreated, including damage to the heart, brain, and other organs. Early detection allows for timely treatment, which can prevent the progression of the disease and protect overall health.

This screening uses a cascade approach, which means it includes multiple tests to confirm a syphilis diagnosis. Initially, a screening test checks for antibodies to the syphilis bacteria. If the first test is positive, additional tests are performed to confirm the diagnosis. This thorough method ensures accurate results, providing individuals with reliable information about their health status.

Who should get this test?

Individuals who are sexually active, especially those with multiple partners
Pregnant women to ensure the health of both mother and baby
People with a history of sexually transmitted infections (STIs)
Individuals experiencing symptoms such as sores, rashes, or unexplained flu-like symptoms
Anyone who wants to know their syphilis status for peace of mind

Benefits of the Treponema Pallidum (Syphilis) Screening Cascade Blood Test:

Early detection: Identifying syphilis early can prevent serious health complications and promote better treatment outcomes.
Accurate results: The cascade approach ensures that individuals receive precise information regarding their syphilis status.
Peace of mind: Knowing your syphilis status can reduce anxiety and help you make informed decisions about your health.
Protects partners: Early diagnosis and treatment help prevent the spread of syphilis to sexual partners.
Supports reproductive health: For pregnant women, this test is vital for ensuring the health of the unborn baby, as syphilis can be transmitted during pregnancy.

LC Sample Report QD Sample Report

CPT Code(s): 86780

Test Code(s):

082345, 90349

Also Known As:

Syphilis Test; Syphilis Antibodies; Trep-Sure™; Treponemal; Reponema Ab; Treponema Pallidum; Reverse Algorithm; T. Pallidum; Treponema Pallidum Antibodies

Specimen:

Blood

Preparation:

No special preparation is required.

Test Results:

2-5 days. May take longer based on weather, holiday, or lab delays.

Details:

(LabCorp Only)This test includes a reflexive RPR test for reactive Treponema pallidum antibody results, which may further reflex to either a quantitative RPR or Treponemal Antibodies (TPPA) test. An interpretation will also be added to assist with result clarity. This screening may not identify early or late-stage syphilis. If you have symptoms or potential exposure concerns, consult your healthcare provider.

(Not Included with LabCorp)This test includes a reflexive RPR Screen for positive Treponema pallidum antibody results. If the RPR Screen is reactive, an RPR Titer will be performed. If the RPR Screen is non-reactive, a Treponema pallidum antibody particle agglutination test will be conducted.