Triiodothyronine (T3) Free Blood Test, Dialysis and LC/MS-MS (Endocrine Sciences)
A T3 free blood test, dialysis and LC/MS-MS is used to evaluate thyroid function and assess abnormal binding protein disorders.
Evaluate thyroid function and assess abnormal binding protein disorders
Direct measurement of FT3 by equilibrium dialysis, high-pressure liquid chromatography, and tandem mass spectrometry (ED-HPLC/MS-MS) provides enhanced accuracy over commonly used analog (automated) methods and is not affected by clinical conditions that impact protein binding capacity.1-4 Examples of clinical conditions in which the FT3 by dialysis and MS/MS method may be preferred include congenital absence of thyroxine-binding protein (TBG);1 pregnancy;1-5 administration of oral contraceptives or hormone therapy;6 administration of atypical antipsychotic medications;7 malignancy or other critical illnesses
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