LabCorp Test

Inflammatory Bowel Disease (IBD) Profile Blood Test

Quick Overview

Blood test to rule out Crohn's disease and ulcerative colitis.

Test #164830

$188.00

Availability: In stock

Also Known As Bowel Disease, Chrohn's Disease, IBD, Ulcerative Colitis
Preparation No special preparation required.
Test Results 2-3 days. May take longer based on weather, holiday or lab delays.



 Inflammatory bowel disease (IBD) is a group of chronic disorders that affect about a million people in the United States. Periods of active disease may alternate with periods of remission. During a flare-up, a patient may experience frequent bouts of watery and/or bloody diarrhea, abdominal pain, weight loss, and fever. Between these flare-ups, symptoms frequently diminish. The cause of IBD is unknown, but these diseases are thought to be due to an autoimmune process that has been triggered by a genetic predisposition, a viral illness, and/or an environmental factor.

  IBD Profile includes: 

Atypical perinuclear antineutrophil cytoplasmic antibodies (pANCA); Saccharomyces cerevisiae, IgA; Saccharomyces cerevisiae, IgG

 

IgA and IgG antibody testing for S cerevisiae is useful adjunct testing for differentiating Crohn's disease and ulcerative colitis. Nearly 80% of Crohn's disease patients are positive for either IgA or IgG. In ulcerative colitis, <15% are positive for IgG, and <2% are positive for IgA. Fewer than 5% of healthy controls are positive for either IgG or IgA antibody, and no healthy controls had antibody for both. The atypical ANCA pattern has been observed in a significant percentage of patients with ulcerative colitis, primary sclerosing cholangitis, and autoimmune hepatitis.

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