Quick Facts
- Sample: Blood
- Fasting: No special preparation is required
- Turnaround: 2-4 days (may take longer based on weather, holiday, or lab delays)
What This Test Measures
This test measures antinuclear antibodies (ANA) in your blood using the immunofluorescence assay (IFA) method. ANA are autoantibodies that mistakenly target proteins found in the nucleus of your cells, and their presence is reported as a positive or negative screening result.
If the screen is positive, the test automatically reflexes to additional measurements: an antibody titer (reported as a ratio, such as 1:160) and the staining pattern produced by the antibodies, such as homogenous, speckled, centromere, or nucleolar. The titer and pattern are only reported when the initial screen is positive.
Benefits
- Screens for antinuclear antibodies linked to autoimmune activity
- Includes automatic reflex titer if the screen is positive
- Identifies staining pattern to support further evaluation
- Uses a single blood draw with no special preparation
- Reports results as a clear positive or negative finding
Who Is This Test For?
- Individuals experiencing unexplained fatigue, rash, or joint pain
- People with symptoms like fever, muscle pain, or swollen glands
- Those with digestive issues or unexplained abdominal pain
- Individuals whose healthcare provider suspects autoimmune activity
- People seeking a starting point for autoimmune symptom evaluation
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. What is the purpose of this test?
This test detects antinuclear antibodies (ANA) in your blood using the IFA method. ANA are autoantibodies that target the nucleus of healthy cells. The result may help a healthcare provider evaluate whether autoimmune activity could be contributing to your symptoms. If the screen is positive, the test automatically adds a titer and pattern result. This test does not diagnose any specific condition on its own.
2. Who would benefit from this test?
People experiencing symptoms often associated with autoimmune activity, such as fatigue, joint pain, rash, or fever, may benefit from this test. It may also be considered by individuals whose healthcare provider wants an initial ANA screening as part of a broader symptom evaluation. This test is not intended for everyone with general health concerns.
3. When should I order this test?
You may consider ordering this test if you are experiencing symptoms commonly linked to autoimmune disorders, such as joint swelling, muscle pain, or unexplained fatigue. It may also be ordered when a healthcare provider wants to begin evaluating possible autoimmune activity. This test is not intended to replace a full medical evaluation.
4. What does this test measure?
This test measures antinuclear antibodies (ANA) in blood using immunofluorescence assay (IFA), reported as a positive or negative screening result. If positive, the test reflexes to a directly measured antibody titer (reported as a ratio) and identifies the staining pattern produced by the antibodies. The titer and pattern results are only generated following a positive screen, not as standalone measurements.
5. Do I need to fast before this test?
No special preparation is required for this test.
6. How quickly will I get results?
Results are typically available in 2-4 days. Results may take longer based on weather, holidays, or lab delays.
7. How do I interpret the results?
A negative result suggests autoantibodies were not detected, while a positive result indicates ANA were present in your blood. The titer and pattern, when reported, provide additional detail but do not confirm a specific diagnosis on their own. Interpretation depends on your symptoms, medical history, medications, and other laboratory findings. Discuss your results with a qualified healthcare provider.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
8. What should I do if my results are abnormal?
If your result is positive, discuss it with a qualified healthcare provider who can evaluate it alongside your symptoms and medical history. Additional evaluation or testing may be considered if recommended by your provider. This result alone does not confirm a diagnosis or indicate the need for treatment.
9. How often should I get tested?
Testing frequency should be determined by your healthcare provider based on your individual symptoms and health history. There is no standard interval established for retesting. Follow your provider's guidance for any follow up testing.
Pre test preparation
No special preparation is required.
