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Angiotensin Converting Enzyme Blood Test

This Angiotensin Converting Enzyme Blood Test is useful in evaluating patients presenting with sarcoidosis, Gaucher's disease and lymphoangiomyomatosis in that the enzyme is increased in these clinical settings.

Sample Report

Test Code: 010116

Also Known As: Serum Angiotensin Converting Enzyme, SACE, ACE

Methodology: Kinetic

Preparation: Stop administration of captopril, enalapril, or lisinopril for 12 hours prior to venipuncture (reduces ACE activity).

Test Results: 3-4 Business days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 683

Also Known As: Serum Angiotensin Converting Enzyme, SACE, ACE

Methodology: Spectrophotometry (SP)

Preparation: Stop administration of captopril, enalapril, or lisinopril for 12 hours prior to venipuncture (reduces ACE activity).

Test Results: 3-5 days. May take longer based on weather, holiday or lab delays.

Description

Angiotensin Converting Enzyme blood test is used to monitor a disease called sarcoidosis. This disease causes granulomas to form in the body, which causes organ inflammation. Organs commonly affected by sarcoidosis include the:

  • lungs
  • liver
  • skin
  • heart
  • eyes
  • spleen
  • lymph nodes

People with sarcoidosis may experience:

  • fatigue
  • joint pain
  • fever
  • dry mouth
  • unexplained weight loss
  • night sweats
  • nosebleeds
  • a loss of appetite
  • swollen lymph nodes

The granulomas associated with sarcoidosis will increase the amount of Angiotensin Converting Enzyme in the bloodstream. 

This test can also be used to assess the effectiveness of treatments for other medical conditions. 

Other conditions that may cause low levels of Angiotensin Converting Enzyme levels include:

  • chronic obstructive pulmonary disease (COPD)
  • emphysema
  • hypothyroidism
  • cystic fibrosis

Conditions that may cause high levels of Angiotensin Converting Enzyme include:

  • cirrhosis
  • hyperthyroidism
  • Gaucher’s disease
  • leprosy
  • psoriasis
  • lymphoma
  • amyloidosis
  • tuberculosis
  • diabetes
  • HIV
  • histoplasmosis

While an ACE level test can help reveal signs of underlying medical conditions, the test is rarely used to diagnose these conditions. Other tests are usually performed along with an Angiotensin Converting Enzyme level test before a diagnosis is confirmed.

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