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Creatine Kinase Isoenzymes (CK Isoenzymes) with Total CK Blood Test

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The Creatine Kinase Isoenzymes (CK Isoenzymes) with Total CK Blood Test checks different forms of an enzyme in your blood to see if there is muscle or heart damage, helping doctors find the cause of symptoms and plan treatment.

LabCorp

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Test Code:

002154

CPT Code(s):

82550,82552

Also Known As:

CK Fractionation ; CK Isoenzymes ; CPK Isoenzymes ; Creatine Phosphokinase Isoenzymes

Methodology:

Total: kinetic; isoenzymes: agarose gel electrophoresis with densitometry

Specimen:

Blood

Preparation:

No special preparation is required.

Test Results:

1-2 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling LabCorp tests to residents in the following states:NY, NJ, RI, MA, MD

Quest

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Sample Report Compare
Test Code:

4451

CPT Code(s):

82550,82552

Also Known As:

CK Fractionation ; CK Isoenzymes ; CPK Isoenzymes ; Creatine Phosphokinase Isoenzymes

Methodology:

Electrophoresis • Enzymatic

Specimen:

Blood

Preparation:

No special preparation is required.

Test Results:

3-5 days. May take longer based on weather, holiday, or lab delays.

Walk-In Lab is prohibited from selling Quest tests to residents in the following states:AZ, NY, NJ, RI


What is the purpose of this test?

The Creatine Kinase Isoenzymes (CK Isoenzymes) with Total CK Blood Test measures different forms of creatine kinase (CK) in your blood. CK is an enzyme found in muscles and heart tissue that helps produce energy for muscle contraction. This test specifically looks at the various forms or isoenzymes of CK, such as CK-MM, CK-MB, and CK-BB. Each form is found in different tissues of the body, with CK-MM predominantly in skeletal muscle, CK-MB in heart muscle, and CK-BB in brain and smooth muscle.

Doctors use the CK Isoenzymes with Total CK Blood Test to diagnose and monitor conditions that affect muscle and heart health. Elevated levels of CK-MM may indicate muscle damage or injury, such as from strenuous exercise or muscle diseases like muscular dystrophy. Elevated levels of CK-MB are often associated with heart muscle damage, such as during a heart attack. By measuring these isoenzymes along with total CK levels, doctors can pinpoint the source of muscle or heart-related symptoms, assess the severity of damage, and guide appropriate treatment strategies.

Who should get this test?

A Creatine Kinase Isoenzymes (CK Isoenzymes) with Total CK Blood Test can benefit individuals who need to evaluate muscle and heart health through specific enzyme levels. Here are the groups of people who would benefit from this test:

  • Athletes and sports enthusiasts: Helps monitor muscle damage due to intense physical activity.
  • People with muscle pain or weakness: Assists in diagnosing conditions like muscular dystrophy or myositis.
  • People with suspected heart attack or chest pain: Helps diagnose heart muscle damage, especially with elevated CK-MB levels.
  • People with autoimmune diseases: Assists in monitoring muscle inflammation associated with conditions like lupus or polymyositis.
  • People with recent trauma or injury: Helps assess muscle damage due to accidents or injuries.
  • People taking medications known to cause muscle damage: Statins and certain drugs can affect CK levels, and the test can monitor for side effects.

These individuals can benefit from a Creatine Kinase Isoenzymes with Total CK Blood Test to understand enzyme levels related to muscle and heart function, guiding appropriate medical management and treatment decisions.

When should I order this test?

An individual should consider ordering a Creatine Kinase Isoenzymes (CK Isoenzymes) with Total CK Blood Test when they experience symptoms that may indicate muscle or heart problems related to enzyme levels. Here are some symptoms to watch for:

  • Muscle pain
  • Muscle weakness
  • Swelling
  • Fatigue
  • Heart-related symptoms
  • Recent trauma or injury
  • Neurological symptoms

If you have these symptoms, discussing them with your doctor can help determine if a Creatine Kinase Isoenzymes with Total CK Blood Test is necessary to assess muscle and heart enzyme levels and investigate potential health conditions.

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