Gliadin Antibody Profile Blood Test, IgA and IgG
Gliadin Antibody Profile, IgG, IgA- detects antigliadin antibodies and aids in the diagnosis and monitoring of certain gluten-sensitive enteropathies, such as celiac disease and dermatitis herpetiformis. Over 100 chronic conditions, including celiac disease, have been associated with increased levels of Antigliadin antibody. Gliadin is the protein component of gluten. Recent research has shown the detection of Antigliadin IgG and IgA to be an indicator of Gliadin involvement in medical conditions.
A gliadin antibodies test is used as part of an evaluation for celiac disease.
Celiac disease is an autoimmune disorder in which the body's immune system mistakenly perceives gluten (found in wheat, barley, rye, and oats) as a foreign invader.
The antibodies are divided into two groups:
- immunoglobulin A (IgA)
- immunoglobulin G (IgG)
IgA is more useful in detecting celiac disease because it's made in the small intestine, where gluten causes inflammation and irritation in sensitive people.
IgG levels are less specific to celiac disease, but may still be useful in diagnosing autoimmune problems, especially in people who are deficient in IgA.
By measuring the levels of both types of gliadin antibodies in the blood, doctors can assess the immune system's response to gluten.
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