Quick Facts
- Sample: Blood and urine
- Fasting: 10–12 hours overnight
- Turn-around: 21 business days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.
Benefits
- Comprehensive insight - Evaluates 150+ biomarkers including 40 amino acids, vitamins, and toxins
- Hidden deficiency detection - Identifies subtle nutrient imbalances before clinical symptoms appear
- Personalized recommendations - Receive tailored supplement and lifestyle guidance with results
- Convenient home testing - No doctor visit required; includes prepaid shipping
- Chronic condition support - Helps address underlying nutritional factors in persistent symptoms
- Baseline and monitoring - Perfect for tracking progress during treatment interventions
Who Is This Test For?
- People with chronic fatigue or unexplained persistent symptoms
- Individuals managing digestive issues, mood disorders, or migraines
- Those seeking to optimize athletic performance or overall wellness
- Anyone wanting a comprehensive nutritional baseline before treatment
- People with cardiovascular risk factors requiring metabolic assessment
- Individuals interested in proactive health management and prevention
How It Works – Just 3 Steps
Order your kit - Simple online ordering with no physician visit required
Collect samples - Provide blood (at draw station) and urine (at home) following kit instructions
Get results - Receive comprehensive report within 21 business days.
FAQ
What does this test measure? This advanced profile analyzes 150+ biomarkers including 40 amino acids, organic acids, fatty acids, vitamins (including CoQ10 and vitamin D), minerals, toxic elements, and oxidative stress markers.
How is this different from standard blood work? Standard labs typically miss functional deficiencies. This test detects subtle nutrient imbalances that can increase chronic disease risk by up to 40% compared to conventional panels (Mayo Clinic 2023).
Do I need a doctor to order this test? No prescription is required to order, but physician follow-up is recommended for abnormal findings or significant deficiencies to develop an appropriate treatment plan.
How should I prepare for testing? Fast for 10-12 hours overnight, continue regular medications unless advised otherwise, and ship samples Monday-Thursday to avoid weekend delays.
When will I get my results? Results are typically available within 21 business days after the laboratory receives your samples, delivered digitally with full confidentiality.
Can I use this to monitor treatment progress? Yes, this test is ideal for baseline assessment and ongoing monitoring. Repeat testing every 6-12 months is often recommended for chronic conditions (AAFP 2022).
More Details
What is the purpose of this test?
The ION Profile provides a comprehensive assessment of your nutritional and metabolic status by measuring over 150 key biomarkers. This advanced analysis evaluates how well your body absorbs, utilizes, and metabolizes essential nutrients while identifying potential toxic exposures. The test reveals functional imbalances that may contribute to chronic symptoms, even when standard blood work appears normal (Cleveland Clinic 2023).
By analyzing 40 different amino acids alongside vitamins, minerals, fatty acids, and organic acids, this profile offers insights into cellular energy production, detoxification capacity, neurotransmitter function, and oxidative stress levels. This comprehensive approach helps identify the root causes of unexplained symptoms and supports personalized treatment strategies.
Who would benefit from this test?
This test is particularly valuable for individuals experiencing chronic fatigue, mood disturbances, digestive issues, migraines, or cardiovascular risk factors that may be linked to nutritional imbalances (AAFP 2022). It's also beneficial for health-conscious individuals seeking to optimize their wellness, athletes looking to enhance performance, or anyone wanting a thorough baseline before starting a new nutrition regimen.
People with complex chronic conditions often find this test helpful when standard labs fail to provide answers. Additionally, those interested in preventive healthcare can use these insights to identify and correct deficiencies before they manifest as clinical symptoms.
When should I order the ION Profile with 40 Amino Acids?
Consider ordering this test when unexplained symptoms persist despite normal standard laboratory results, or when you're starting a new nutrition or supplementation regimen and want baseline measurements (Mayo Clinic 2023). It's also valuable for monitoring known chronic conditions or optimizing long-term health strategies.
This test is particularly useful if you're working with a healthcare provider on complex health issues, want to personalize your nutrition approach, or are curious about your body's unique nutritional needs and metabolic function.
How do I interpret the results?
Amino Acids
- What it means: Protein metabolism and neurotransmitter function
- Typical action: Adjust protein intake or specific amino acid supplementation
Organic Acids
- What it means: Cellular energy production and detoxification
- Typical action: Support mitochondrial function and metabolic pathways
Fatty Acids
- What it means: Inflammation status and membrane health
- Typical action: Modify dietary fats or omega-3 supplementation
Vitamins/Minerals
- What it means: Micronutrient sufficiency for enzymatic functions
- Typical action: Targeted supplementation or dietary changes
Toxic Elements
- What it means: Heavy metal or environmental toxin exposure
- Typical action: Detoxification support and exposure reduction
The report groups findings by functional category and includes personalized recommendations for diet, supplements, and lifestyle modifications based on your unique results.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
Pre-test preparation
Fast for 10-12 hours overnight before sample collection, typically stopping food and beverages (except water) after dinner the night before. Continue taking your regular medications unless specifically instructed otherwise by your healthcare provider. Plan to ship your samples Monday through Thursday to avoid weekend delays that could affect sample integrity.
Ensure you have access to a blood draw station for the blood collection portion, as this requires professional phlebotomy services while the urine sample can be collected at home following the detailed kit instructions.
How often should I get tested?
- Initial baseline assessment: Once, then repeat in 6–12 months
- Active treatment monitoring: Every 6 months
- Chronic condition management: Every 6–12 months
- Preventive health optimization: Every 1–2 years
- Post-intervention follow-up: 3–6 months after changes
Why early detection matters
Over 30% of US adults have at least one micronutrient deficiency despite following normal diets (CDC 2019). Functional imbalances detectable through comprehensive metabolic testing are associated with increased risk of mood disorders, fatigue syndromes, and cardiovascular disease (Cleveland Clinic 2023).
Early correction of nutrient deficiencies can reduce lifelong chronic disease risk and lower overall medical costs by an estimated 15% (Johns Hopkins 2024). By identifying and addressing imbalances before they progress to clinical symptoms, you can take proactive steps toward optimal health and prevent future complications.
Related tests you may consider
Comprehensive Metabolic Panel (CMP-14) with eGFR Blood Test - Evaluates nutrient levels, liver, and kidney function.
Micronutrients, B-Vitamin Blood Test Panel - Measures levels of B-vitamins to identify deficiencies that may cause health problems.
Food Sensitivities and Gut Imbalance Panel - Mosaic Diagnostics Test Kit - Checks for food sensitivities and gut imbalances by measuring 76 organic acids and antibodies to 190 foods, herbs, and yeast, helping create a personalized plan to improve digestion, energy, and overall health.
