Quick Facts
- Sample: Blood + Urine
- Fasting: Fasting for at least 12 hours is required.
- Turnaround: 2-3 business days. May take longer based on weather, holiday, or lab delays.
What's Included
Antinuclear Antibodies (ANA), IFA with Reflex to Titer and Pattern
- ANA Screen, IFA: Detects antinuclear antibodies in the blood using indirect immunofluorescence. Results are reported as positive or negative.
- ANA Titer (Reflex Testing): Measures the highest dilution of a blood sample at which antinuclear antibodies remain detectable. Performed when the ANA screen is positive.
- ANA Pattern (Reflex Testing): Identifies the fluorescence pattern produced by antinuclear antibodies, which may help evaluate autoimmune disorders. Performed when the ANA screen is positive.
Important: The ANA test included in this panel varies by laboratory. Reference ranges, pattern classifications, and result reporting may differ between laboratories. Additional ANA patterns and corresponding titers may be reported when detected. Results should be interpreted alongside symptoms, medical history, and other laboratory findings.
Complete Blood Count (CBC) with Differential and Platelets Blood Test
White Blood Cells
Red Blood Cells and Red Cell Indices
- Red Blood Cells (RBC): Carries oxygen and carbon dioxide to and from your cells. Iron deficiency can lower this count.
- Hemoglobin: A compound inside red cells that carries oxygen through your bloodstream and gives blood its red color.
- Hematocrit: The percentage of blood volume made up of red blood cells.
- MCH (Mean Corpuscular Hemoglobin): The average hemoglobin amount within a single red blood cell.
- MCHC (Mean Corpuscular Hemoglobin Concentration): The average hemoglobin concentration percentage within a red blood cell.
- MCV (Mean Corpuscular Volume): The average size of your red blood cells.
- RDW (Red Cell Distribution Width): Measures the variation in volume and size among your red blood cells.
Platelets
- Platelet Count: Blood cell particles that play a role in forming blood clots.
- MPV (Mean Platelet Volume): The average size of platelets in the blood, providing information about platelet production and activity.
White Blood Cell Differential
- Neutrophils: The most common white blood cell type, created by your bone marrow to combat inflammatory and infectious conditions.
- Lymphocytes: B cells and T cells that fight bacteria and other pathogens, found mainly in your lymph system.
- Monocytes: Work alongside neutrophils to fight infections and clear away dead or damaged cells.
- Eos (Eosinophils): White blood cells that become active in response to allergies and certain infections.
- Basophils: Help detect infections early, support wound healing, and respond to allergic reactions.
- Immature Granulocytes: A component of your white blood cell differential included in this panel. (Labcorp only)
Urinalysis, Complete with a Microscopic Examination
- Specific Gravity: The concentration of the urine sample. This is used to help evaluate the level of certain substances dissolved in the urine. Low specific gravity can result from ingesting large amounts of water before urination.
- pH: This is affected by the acid/base balance in the body. A pH that is too high or low can form crystals in the urine, leading to the development of kidney stones. PH can be adjusted through diet or medication.
- Color: Darker urine coloration can result from some medications, eating certain foods, blood in the urine, dehydration, or fever
- Appearance: Bacteria, red blood cells, white blood cells, mucus, or contaminants such as lotions or powders may cause cloudy or turbid urine.
- WBC Esterase: White blood cells in the urine typically indicate a bacterial urinary tract infection. It may also be caused by inflammation in the kidneys.
- Protein: The amount of albumin in the urine. Protein in the urine can indicate kidney disease or conditions affecting the urinary tract.
- Glucose: Glucose in the urine can be a sign of abnormally high blood sugar levels, such as those caused by diabetes.
- Ketones: Ketones are produced when the body metabolizes fat. They can indicate several conditions, including starvation, a high protein/low carbohydrate diet, diabetes, or frequent vomiting.
- Occult Blood: Blood in the urine can indicate several conditions affecting the kidneys or urinary tract. It can also be caused by contamination from sources such as menstruation, hemorrhoids, or vaginal bleeding.
- Bilirubin: Bilirubin is a waste product produced by the liver. Bilirubin in urine can be an early indicator of liver disease.
- Urobilinogen: Urobilinogen is formed from Bilirubin. Its presence in urine is typically a sign of liver disease. (LabCorp Only)
- Nitrite: Nitrite in the urine is usually caused by bacteria, which can indicate a urinary tract infection.
- Microscopic Examination
- A microscopic examination will automatically be performed if any abnormalities are detected in the initial urinalysis. The microscopic examination may include some or all of the following if the results warrant:
- White Blood Cells (WBCs): WBCs in urine usually indicate inflammation or infection of the urinary tract.
- Red Blood Cells (RBC): RBCs in urine can be caused by inflammation or injury to the kidneys or urinary tract.
- Epithelial Cells: High concentrations of epithelial cells are typically caused by infection or inflammation of the urinary tract.
- Crystals: Crystals may be formed by various particles dissolved in urine. Crystal formation may be due to an abnormal pH balance or a higher-than-normal concentration of particles. Crystals formed in the kidneys may lead to the development of kidney stones.
- Casts: Casts are cylindrical particles formed from proteins secreted by the kidneys. In people with kidney disease, substances such as RBCs or WBCs may become trapped in the proteins. Examining the casts can help differentiate between types of kidney disorders.
- Mucus: Mucus in the urine may result from a urinary tract infection or conditions affecting the digestive system, specific STDs, or kidney disease.
- Bacteria: Bacteria in the urine usually indicate a urinary tract infection. Care should be taken to avoid contaminating the specimen with bacteria from the genital area or hands.
Rheumatoid Arthritis (RA) Factor
Sedimentation Rate (ESR) Westergren
C-Reactive Protein (CRP) High Sensitivity Cardiac Risk
Comprehensive Metabolic Panel (CMP-14)
Blood Sugar
Kidney Profile
- BUN (Blood Urea Nitrogen): A waste product formed when the body breaks down protein, normally removed by the kidneys.
- Creatinine, Serum: A waste product from normal muscle activity that is filtered from the blood by the kidneys.
- BUN/Creatinine Ratio: A calculated value (BUN divided by creatinine) that can suggest conditions like dehydration or intestinal bleeding.
- Estimated Glomerular Filtration Rate (eGFR): A calculated estimate of how effectively the kidneys filter waste from the blood, used to assess kidney function.
Liver Panel
- Protein, Total: The combined amount of albumin and globulin proteins in the blood, which helps assess liver and kidney function and nutritional health.
- Albumin, Serum: A protein produced by the liver that helps maintain fluid balance and transport substances through the blood.
- Globulin, Total: A group of blood proteins involved in immune defense, transporting substances, and other important body functions.
- Albumin/Globulin Ratio: A calculated value (albumin divided by globulin) that, alongside other results, can assist in evaluating liver problems.
- Bilirubin, Total: A yellow pigment produced during the normal breakdown of red blood cells and processed by the liver. Elevated levels can cause jaundice.
- Alkaline Phosphatase: An enzyme found primarily in the liver, bile ducts, and bones that can help identify liver or bone disorders.
- Aspartate Aminotransferase (AST or SGOT): An enzyme found in the liver and other tissues, such as the heart and muscles, that is released into the blood when cells are damaged.
- Alanine Aminotransferase (ALT or SGPT): An enzyme that helps identify liver damage. Abnormal levels may represent liver disease.
Fluids & Electrolytes
- Sodium: One of the major salts in your body fluid, important for water balance and the electrical activity of nerves and muscles.
- Potassium: Helps control the function of your nerves and muscles.
- Chloride: Similar to sodium, it helps maintain your body's electrolyte balance.
- Carbon Dioxide, Total: A measure that primarily reflects bicarbonate in the blood, helping assess the body's acid-base balance.
- Calcium: A mineral essential for developing and maintaining healthy bones and teeth, and for normal muscle, nerve, and blood clotting function.
Prothrombin Time (PT) and Partial Thromboplastin Time (PTT)
- Prothrombin Time (PT): Measures clotting time along the extrinsic and common pathways.
- INR: A standardized value calculated from your PT result.
- Partial Thromboplastin Time, Activated (PTT): Measures clotting time along the intrinsic and common pathways.
Benefits
- Screens for autoimmune antibody activity using the ANA test.
- Reviews red and white blood cell counts and platelets.
- Assesses kidney and liver function markers together.
- Measures inflammation through ESR, CRP, and RA factor.
- Evaluates urine for kidney related and metabolic changes.
- Reviews blood clotting time through PT and PTT.
Who Is This Test For?
- Individuals who want a broader look at immune related blood markers.
- Individuals experiencing joint discomfort, fatigue, or skin changes they want assessed.
- Individuals whose healthcare provider has recommended autoimmune related screening.
- Individuals monitoring existing autoimmune related concerns over time.
- Individuals following up on previous antibody or inflammation related results.
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. What is the purpose of this test?
This panel combines several blood and urine based tests to help evaluate immune system activity. It includes the ANA test, a complete blood count, urinalysis, RA factor, ESR, CRP, a comprehensive metabolic panel, and clotting time tests. Together, these results give your healthcare provider a broader picture of immune, kidney, liver, and clotting related function to consider alongside your symptoms and history. It is intended to provide information for you and your healthcare provider, not to diagnose a condition on its own.
2. Who would benefit from this test, and when should I order it?
This panel may be useful if you want a broader look at immune, kidney, liver, and inflammation related markers, such as part of a broader health check. It may also be appropriate if your healthcare provider has suggested autoimmune related screening, or if you are following up on previous antibody or inflammation related results.
3. Do I need to fast before this test?
Yes. Fasting for at least 12 hours is required before this test.
4. How quickly will I get results?
Results are typically available in 2-3 business days. Results may take longer based on weather, holiday, or lab delays.
5. How do I interpret the results?
Your results include many individual biomarkers, and patterns across these markers are often more meaningful than any single value on its own. Rather than interpreting one result in isolation, your healthcare provider can review the full panel alongside your symptoms and medical history to help make sense of what the results may mean for you.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
6. What should I do if my results are abnormal?
If any of your results fall outside the expected range, share them with your healthcare provider. They can help determine whether any follow up steps are needed.
7. How often should I get tested, and why does ongoing monitoring matter?
There is no single testing schedule that fits everyone. How often to repeat this panel depends on your individual health history and goals, so it's best to test as directed by your healthcare provider. Reviewing immune, blood cell, kidney, liver, and inflammation related markers over time may help support earlier awareness of changes in these systems. This panel is intended to support ongoing monitoring and conversations with your healthcare provider, not to guarantee detection of any specific condition.
Pre-test preparation
Fasting for at least 12 hours is required.
