Protein Electrophoresis Urine Test, Random

What is the purpose of this test?

The Protein Electrophoresis Urine Test, Random, is used to evaluate and identify abnormal proteins in the urine. This test uses a technique calledelectrophoresis to separate different types of proteins based on their electrical charge and size. It is especially helpful in detecting monoclonal proteins (M-proteins), which may be associated with serious conditions such as multiple myeloma, Waldenström’s macroglobulinemia, and other plasma cell disorders. Unlike 24-hour urine collection, this test uses a random sample, making it more convenient while still offering valuable diagnostic insights.

This test can also detect proteinuria, which occurs when the kidneys allow abnormal amounts of protein to pass into the urine. Proteinuria may be a sign ofkidney damage, chronic kidney disease (CKD), or glomerulonephritis. By identifying and characterizing the specific types of proteins present in urine, this test helps differentiate between different kidney and immune system conditions, guiding doctors in diagnosis and treatment decisions. When used alongside blood and other urine tests, it plays an important role in monitoring disease progression and evaluating response to treatment.

Who should get this test?

The Protein Electrophoresis Urine Test, Random may benefit:

• Individuals with suspected or confirmed multiple myeloma or other plasma cell disorders
• Patients with unexplained protein in the urine (proteinuria)
• People with chronic kidney disease or suspected kidney damage
• Individuals with unexplained fatigue, bone pain, or frequent infections
• Those being monitored for monoclonal gammopathies
• Patients experiencing symptoms related to autoimmune disorders
• People with abnormal blood protein test results
• Individuals with a family history of myeloma or B-cell lymphomas

When should I order the Protein Electrophoresis Urine Test, Random?

Individuals may consider ordering this test if they are experiencing symptoms that could be related to abnormal protein levels in the urine.

Symptoms to consider:

• Swelling in the legs, ankles, or around the eyes (edema)
• Foamy or bubbly urine
• Fatigue or general weakness
• Frequent infections
• Bone pain or tenderness
• Unexplained weight loss
• Blood in the urine

If you have these symptoms, the Protein Electrophoresis Urine Test, Random can help detect abnormal proteins and guide you and your doctor in diagnosing conditions such as multiple myeloma, kidney disease, or other protein disorders.