Thyroid #4 Comprehensive Blood Test Panel

Quick Facts

• Sample: Blood
• Fasting: No fasting required. Stop biotin consumption at least 72 hours before your collection. Avoid collection during or after heparin administration.
• Turnaround: 4-6 business days. May take longer based on weather, holiday, or lab delays.

What's Included

Thyroid Panel with TSH

• Thyroid-Stimulating Hormone (TSH): Measures the hormone produced by the pituitary gland that regulates thyroid hormone production. Helps evaluate thyroid function and identify potential thyroid disorders.
• T3 Uptake: Measures thyroid hormone-binding capacity and helps evaluate thyroid function when used alongside total T4.
• T4 (Thyroxine), Total: Measures the total amount of thyroxine in the blood, including both bound and unbound forms, to help assess thyroid function.
• Free Thyroxine Index (T7): A calculated value derived from total T4 and T3 uptake that helps estimate free thyroid hormone levels.

T4, Free

• Thyroxine (T4), Free (Direct): Measures the amount of unbound thyroxine available for the body to use. Helps evaluate thyroid function and diagnose thyroid disorders.

T3, Free

• Triiodothyronine (T3), Free: Measures the amount of unbound T3 available to the body's tissues. Helps assess thyroid function, particularly when hyperthyroidism is suspected.

Thyroid Peroxidase (TPO) Antibodies

• Thyroid Peroxidase (TPO) Antibodies: Detects antibodies against thyroid peroxidase, an enzyme involved in thyroid hormone production. Helps identify autoimmune thyroid conditions, including Hashimoto's thyroiditis.

Thyroglobulin Antibodies (TAA)

• Thyroid Antithyroglobulin Antibody: Detects antibodies against thyroglobulin, a protein involved in thyroid hormone production. Helps evaluate autoimmune thyroid conditions.

Reverse T3

• Reverse T3, Serum: A biologically inactive form of T3. Levels can rise during stress, severe illness, injury, or with certain drugs (such as amiodarone and glucocorticoids). May be evaluated alongside Free T3, although reverse T3 testing is not routinely recommended for diagnosing thyroid disorders.

Thyroxine Binding Globulin (TBG)

• Thyroxine Binding Globulin (TBG): Measures the primary protein responsible for transporting thyroid hormones in the blood. Helps determine whether abnormal thyroid hormone levels may be related to changes in binding proteins.

Thyroid Stimulating Immunoglobulin (TSI)

• Thyroid Stimulating Immunoglobulin (TSI): Detects antibodies that stimulate the thyroid gland to produce excess thyroid hormones. Helps evaluate Graves' disease and other causes of hyperthyroidism.

T3, Total

• Triiodothyronine (T3), Total: Measures the total amount of T3 in the blood, including bound and unbound forms. Helps evaluate thyroid function and investigate hyperthyroidism.

Benefits

• Evaluates thyroid hormones, antibodies, and binding proteins in one panel.
• Supports a broader picture of overall thyroid function.
• Includes markers relevant to autoimmune thyroid conditions.
• Helps distinguish true hormone changes from binding protein effects.
• Convenient blood draw with no fasting required.

Who Is This Test For?

• Individuals interested in a comprehensive look at their thyroid function.
• People whose prior thyroid results seemed inconsistent with symptoms.
• Those with a personal or family history of thyroid or autoimmune conditions.
• Individuals monitoring thyroid health alongside a healthcare provider.
• People wanting insight into thyroid antibodies as well as hormone levels.

How It Works

1. Order Your Test Online
2. Visit a Local Lab
3. Get Results Online

FAQ

1. What is the purpose of this panel?

This panel measures thyroid hormone markers (TSH, Free T3, Free T4, Total T3, T4, T3 Uptake, and Free T4 Index), thyroid antibodies (TPO, antithyroglobulin, and TSI), and binding-related markers (TBG and Reverse T3). Together, these results provide a broader view of thyroid function and possible autoimmune activity. This panel does not diagnose a specific condition on its own.

2. When might I consider ordering this panel?

You may consider this panel for a thorough thyroid evaluation, to follow up on inconsistent or unclear thyroid results, or for ongoing monitoring of thyroid activity. It may also be useful for people with a personal or family history of thyroid or autoimmune conditions.

3. Do I need to fast or prepare before this test?

Fasting is not required. Stop taking biotin at least 72 hours before collection, and do not collect the sample during or after heparin administration.

4. How quickly will I get results?

Results are typically available in 4–6 days. Weather, holidays, or laboratory delays may extend this timeframe.

5. How do I interpret the results?

Thyroid results are often more meaningful when viewed together as a pattern rather than as individual values. Hormone, antibody, and binding-related markers can influence one another, so a healthcare provider is best placed to interpret the results in the context of your overall health.

Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.

6. What should I do if my results are outside the expected range?

Share your results with your healthcare provider. They can explain what they may mean for you and determine whether additional evaluation or follow-up testing is appropriate.

7. How often should I get tested?

Testing frequency depends on your health history and goals. Follow your healthcare provider’s guidance for monitoring thyroid function over time.

Pre-test preparation

No fasting is required. Stop biotin consumption at least 72 hours prior to the collection. Collection should not occur during or after heparin administration.

Do not stop prescribed medication unless instructed by your healthcare provider.