All Products > Autoimmune Tests > Celiac Disease

Tissue Transglutaminase (tTG) Blood Test, IgA

Link copied!

A tTG blood test detects antibodies to aid in the diagnosis of gluten-sensitive enteropathy (GSE), such as celiac disease and dermatitis herpetiformis.

Compare

Tissue transglutaminase antibody (tTG), IgA, is the primary test ordered to screen for celiac disease. It is the most sensitive and specific blood test for celiac disease and is the single test preferred by the American College of Gastroenterology, according to its 2013 guidelines, as well as the American Gastroenterology Association for the detection of celiac disease in those over the age of 2 years.

Studies have demonstrated that IgA endomysial antibody tests have >99% specificity for gluten-sensitive enteropathy. Recently, the endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase (tTG).

tTG IgA is used for:

Evaluating patients suspected of having celiac disease, including patients with compatible clinical symptoms, patients with atypical symptoms, and individuals at increased risk (family history, previous diagnosis with associated disorder, positivity for HLA DQ2 and/or DQ8)

Screening test for dermatitis herpetiformis, in conjunction with endomysial antibody test

Monitoring adherence to gluten-free diet in patients with dermatitis herpetiformis and celiac disease

LC Sample Report QD Sample Report

Test Code(s):

164640, 8821

Also Known As:

Celiac Disease; tTG Antibody; Transglutaminase; Tissue Antibody IgA; Dermatitis Herpetiformis; tTG IgA; IgA anti-tissue transglutaminase; IgA Anti-tTG

Specimen:

Blood

Preparation:

No special preparation required.

Test Results:

4-10 days. May take longer based on weather, holiday or lab delays.

The Tissue Transglutaminase (tTG) Blood Test, IgG, checks for specific antibodies to help diagnose celiac disease and guide treatment by identifying if your immune system is reacting to gluten.

Celiac Disease Comprehensive Antibody Profile Blood ...

The Celiac Disease Comprehensive Antibody Profile Blood Test measures the IgA or IgG antibody levels to diagnose celiac disease and monitor response to dietary changes.

Celiac Disease Profile II Blood Test

The Celiac Disease Profile II Blood Test checks for certain antibodies in your blood to help find out if you have celiac disease, a condition where eating gluten causes your immune system to attack your small intestine, leading to symptoms like stomach pain, tiredness, rashes, or weight loss, and it helps your doctor decide if you need further testing or a gluten-free diet.