Anemia #2 Essential Blood Test Panel
An Anemia #2 Essential Blood Test Panel includes Iron w/TIBC, Transferrin, Ferritin, Complete Blood Count (CBC), Comprehensive Metabolic Panel (CMP-14), Vitamin B12, Folic Acid and Hemoglobin Solubility.
The Iron and Total Iron-binding Capacity test is used for testing differential diagnosis of anemia, evaluation of thalassemia and possible sideroblastic anemia, and the evaluation of iron poisoning. Specimen collection must be done before a patient is given therapeutic iron or blood transfusion. Iron determinations on patients who have had blood transfusions should be delayed at least four days.
Ferritin is a protein in the body that binds to iron, most iron stored in the body is bound to ferritin. It is found in the liver, skeletal muscles, spleen, and bone marrow. There is only a small amount of ferritin that is found in the blood, and the amount of ferritin in the blood shows how much iron is stored in your body.
Transferrin tests the plasma protein that binds to iron and then transports it through the circulation. TIBC measures the total amount of iron that the transferrin can bind. The two tests are different and are reported in different units (g/L for transferrin and umol/L for TIBC), they essentially measure the same thing. Transferrin blood levels are used to evaluate iron deficiency and anemia. High transferrin levels are found in pregnancy, iron deficiency, and in those taking birth control pills. It is low in cancer, liver disease, kidney disease, chronic inflammation, hereditary transferrin deficiency, or when there are excessive amounts of iron in the body.
A Complete Blood Count (CBC) gives important information about the numbers and kinds of cells in the blood, especially red blood cells, white blood cells, and platelets. A CBC helps your health professional check any symptoms, such as fatigue, weakness, or bruising, that you may have. A CBC also helps your health professional diagnose conditions, such as infection, anemia, and several other disorders. Test includes: WBC, RBC, Hemoglobin, Hematocrit, MCV, MCH, MCHC, RDW, Platelets, Neutrophils, Lymphs, Monocytes, Eos, Basos, Neutrophils (Absolute), Lymphs (Absolute), Monocytes (Absolute), Eos (Absolute), Basos (Absolute), Immature Granulocytes, Immature Grans (Abs)
Glucose (blood sugar level) - The most direct test to diagnose diabetes, may be used not only to identify diabetes but also to evaluate how one controls the disease.
Bun or Urea Nitrogen - A by-product of protein metabolism eliminated through the kidneys, BUN is an indicator of kidney function. Creatinine, Serum indicates kidney function.
Bun/Creatinine Ratio - Calculated by dividing the BUN by the Creatinine.
Glomerular Filtration (eGFR) - Provides an assessment of the kidney's filtering capacity.
Fluids & Electrolytes
Sodium - Important in the body's water balance and the electrical activity of nerves and muscles and one of the major salts in body fluid.
Potassium - Helps to control the muscles and nerves.
Chloride - Similar to sodium, chloride helps to maintain the body's electrolyte balance.
Carbon Dioxide - Total Used in detecting, evaluating, and monitoring electrolyte imbalances.
Calcium - A mineral essential for development and maintenance of healthy teeth and bones. It is important also for the normal function of nerves, muscles and blood clotting.
Protein, Total - A measure of the state of nutrition in the body together with albumin.
Albumin Serum - A major protein in the blood and a reflection of the general state of nutrition.
Globulin, Total - A major group of proteins in the blood that comprises the infection-fighting antibodies.
Albumin/Globulin Ratio - Calculated by dividing the albumin by the globulin.
Bilirubin, Total - A chemical that is involved with liver functions. High concentrations of bilirubin may result in jaundice.
Alkaline Phosphatase - A body protein that is important in diagnosing proper bone and liver functions.
Aspartate Aminotransferase (AST or SGOT) - An enzyme that is found in skeletal and heart muscle, liver, and other organs. Abnormalities may represent liver disease.
Alanine Aminotransferase (ALT or SGPT) - An enzyme that is found primarily in the liver. Abnormalities may represent liver disease.
Vitamin B12 - Help to diagnose the causes of anemia and neuropathy (nerve damage), evaluate nutritional status in some, and monitor the effectiveness of B12 deficiency or folate deficiency treatment. B12 and folate are primarily ordered to diagnose the cause of macrocytic anemia.
Folic Acid - Detects folate deficiency and monitor folate deficiency therapy. Folic acid levels are ordinarily measured with red cell folates and vitamin B12 levels. Measurement of both red cell folate levels and serum constitutes a reliable means of determining the existence of folate deficiency. Folic Acid tests are recommended for patients with anemia, as B12 and folate are primarily ordered to help diagnose the cause of macrocytic anemia.
Hemoglobin Solubility - Qualitative determination of the presence of hemoglobin S; detect sickling hemoglobins; evaluate hemolytic anemia, undiagnosed hereditary anemia with morphologic (sickle-like) abnormalities on peripheral blood smear
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