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Anti-Aging #4 Comprehensive Blood and Urine Test Panel, Women

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An Anti-Aging #4 Comprehensive Blood and Urine Test Panel for Women includes a Wellness #2 Essential Panel (CBC, CMP-14, Glucose, Uric Acid, Lipid Profile, Thyroid + TSH, Fluid & Electrolytes, Mineral & Bone, Liver & Kidney Panels), Insulin-like Growth Factor 1, Testosterone Total & Free, Urinalysis with Complete Microscopic Examination, Vitamin D 25-Hydroxy, Iron w/TBIC, Estradiol, DHEAs, Human Growth Hormone (HGH), Progesterone, Hemoglobin A1C, Free T4, Free T3, Homocysteine and C-reactive Protein, hs (Cardiac) plus Vitamin A, Follicle-stimulating Hormone (FSH) & Luteinizing Hormone (LH), Vitamin B12, Folate (Folic Acid), NMR LipoProfile, Sex Hormone Binding Globulin (SHBG), and Cortisol Random.


Test Code: 853

CPT Code: See Individual Tests

Also Known As:

Methodology:

Preparation:

Patient should be on a stable diet, ideally for two to three weeks prior to collection of blood, and should fast for 12 to 14 hours before collection of the specimen. Refrain from consuming alcohol 24 hours before the collection and biotin for at least 72 hours prior to the collection. Resting is required for at least 30 minutes prior to collection. Must draw before Schilling test, transfusions or B12 therapy is started. Collection should not occur during or after administration of heparin.

Test Results:

3-5 days. May take longer based on weather, holiday or lab delays.


Details:

Please note: Any result for the Testosterone Free (Direct) and Total Testosterone Test in excess of 1500 will be reported as >1500

Description

Anti-aging medicine is a specialty founded on the application of advanced scientific and medical technologies for the early detection, prevention, treatment, and reversal of age-related diseases. Research into ways to optimize and retard the human aging process is designed to prolong the human life span. Anti-aging medicine is a specialty based on the scientific principles of responsible medical care consistent with those of other healthcare specialties.

 

Included in this panel:

 

The Wellness #2 Essential Blood Test Panel includes:

  • Comprehensive Metabolic Panel (CMP-14) with eGRF Blood Test
    • Glucose Level
    • Kidney Profile
    • Liver Panel
    • Fluids and Electrolytes
    • Mineral and Bone
  • Lipid Panel With Total Cholesterol:HDL Ratio
  • Thyroid Panel with Thyroid-stimulating Hormone (TSH)
  • Complete Blood Count (CBC) With Differential & Platelets

 

Comprehensive Metabolic Panel (CMP-14) with eGRF Blood Test

  • Glucose - Blood sugar level, the most direct test to screen for diabetes and also used in diabetes management.

 

  • Uric Acid - Uric acid is produced in two ways, from digesting food consumed and the natural breakdown of the body's cells. Uric acid is a by-product of protein metabolism eliminated through the kidneys. It is also an indicator of kidney function.

 

  • Kidney Profile
    • Bun or Urea Nitrogen (BUN) - An indicator of kidney function.  
    • Creatinine, Serum - An indicator of kidney function. 
    • Bun/Creatinine Ratio - Calculated by dividing BUN by creatinine. This ratio can suggest conditions including dehydration or intestinal bleeding.
    • Estimated Glomerular Filtration Rate (eGFR) - Measures kidney function to determine kidney disease stage and detect early kidney damage.

 

  • Liver Panel
    • Protein, Total - Assists in determining liver and kidney function and nutritional health.
    • Albumin Serum - One of the major proteins essential for the healthy function of the liver and kidney.
    • Globulin, Total - One of the major proteins that assist the blood to clot properly and also comprises infection-fighting antibodies.
    • Albumin/Globulin Ratio - Calculated by dividing albumin by globulin. When paired with other test results, this ratio can assist in the diagnosis of a variety of liver problems.
    • Bilirubin, Total - Aids in the detection of hepatitis, sickle cell, anemia, cirrhosis, alcohol, and drug abuse. High concentrations may result in jaundice.
    • Alkaline Phosphatase - A protein vital in detecting bone disorders and liver disease.
    • Aspartate Aminotransferase (AST or SGOT) - An enzyme helpful in evaluating liver function. An elevated level is an indication of hepatitis.
    • Alanine Aminotransferase (ALT or SGPT) - An enzyme helpful in identifying liver damage. Abnormalities may represent liver disease.
    • Lactate Dehydrogenase (LDH) - An enzyme found mainly in the heart, muscles, liver, kidney, brain, and red blood cells. When an organ of the body is damaged, LDH is released in more significant quantities into the bloodstream.
    • Gamma-Glutamyl Transferase (GGT) - Also known as Gamma-Glutamyl Transpeptidase (GGTP). GGT is an enzyme that is produced predominantly in the liver. This level is often elevated in situations that diseases are present that affect the liver or bile ducts.

 

  • Fluids & Electrolytes
    • Sodium - One of the major salts in body fluid. Sodium is important in water balance and the electrical activity of nerves and muscles.
    • Potassium - Helps to control the nerves and muscles.
    • Chloride - Similar to sodium, it helps to maintain the body's electrolyte balance.
    • Carbon Dioxide, Total - Used to help detect, evaluate, and monitor electrolyte imbalances.

 

  • Mineral and Bone
    • Iron, Total - An abnormally low test result could indicate anemia caused by iron deficiency.
    • Calcium - A mineral essential for the development and maintenance of healthy bones and teeth. It is also important for the normal function of muscles, nerves, and blood clotting.
    • Phosphorus - A crucial mineral for energy production, muscle and nerve function, and bone formation. Most of the body's phosphorus mixes with calcium to form teeth and bones. Phosphorus is also important for keeping the body's acid-base balanced.

 

Lipid Panel With Total Cholesterol:HDL Ratio

  • Cholesterol, Total - A measurement used to assess heart health. Cholesterol is required by your body to build healthy cells, but high cholesterol levels can increase your risk of heart disease.
  • Triglycerides - Surplus fats that are transported in the bloodstream and are also responsible for providing energy to the body.
  • HDL Cholesterol - High-density lipoproteins, or "good" cholesterol, take cholesterol away from the cells and transport it back to the liver for removal or processing.
  • LDL Cholesterol - Low-density lipoproteins (calculation), or "bad" cholesterol, contain the highest percentage of cholesterol and are responsible for depositing cholesterol on the artery walls.
  • Total Cholesterol/HDL Ratio - This ratio is calculated by dividing total cholesterol by HDL cholesterol and is used in determining the relative risk of heart disease.

 

Thyroid Panel with Thyroid-Stimulating Hormone (TSH)

The thyroid gland synthesizes, stores, and releases hormones. The hormones secreted are iodine-containing amino acids, thyroxine (T4), and tri-iodothyronine (T3). The thyroid hormones influence various metabolic processes, including weight control, energy level, and heart rate. This comprehensive test helps to evaluate thyroid hormones that control the body's metabolic rate and includes: Total T4 (Thyroxine), T3 Uptake, Free-Thyroxine Index (FTI), also known as T7, and Thyroid-Stimulating Hormone (TSH).

 

Insulin-like Growth Factor Test (IGF-1)

Produced in the liver in response to stimulation by growth hormones secreted by the pituitary gland. This insulin-like growth factor level is used to evaluate disturbances of growth and monitor treatment with growth hormones.

 

Testosterone, Total

Testosterone is a hormone that causes male characteristics. The blood level is used in men to investigate abnormal sexual development and sexual dysfunction. Small amounts are produced in women's ovaries, and levels are tested to evaluate virilization.

 

Urinalysis with Complete Microscopic Examination

Detects urine and urinary tract infections (UTI); diagnoses and manages renal diseases, urinary tract infections, urinary tract neoplasms, systemic diseases, and inflammatory or neoplastic diseases adjacent to the urinary tract.

 

Vitamin D 25-hydroxy

Vitamin D is essential for the growth and formation of healthy bones and teeth. Without it, adults can develop osteomalacia, characterized by weakness, softness, or fractures of the bones. Vitamin D also helps regulate levels of calcium, phosphorus, and magnesium in the blood and has been shown to influence the growth of other tissues in the body and the regulation of the immune system. Vitamin D deficiency has been implicated in the development of conditions such as cancer, heart disease‚ osteoporosis, and multiple sclerosis.

 

The body gets vitamin D from two sources: dietary intake through foods and supplements (exogenous) and through production in the skin upon exposure to sunlight (endogenous). Although vitamin D is found naturally in only a few foods, in the United States, many products are supplemented with it, including milk, breakfast cereals, and juices. Those at risk of vitamin D deficiency include individuals that are elderly, obese, dark skin, institutionalized, homebound or have limited sun exposure, have undergone gastric bypass surgery, and have conditions such as cystic fibrosis and Crohn's disease that interfere with fat absorption.

 

Iron and Total Iron-binding Capacity (TIBC)

The iron and TIBC blood test quantifies iron serum and total iron-binding capacity (TIBC). Iron serum measures iron levels in the blood, while TIBC measures the total amount of iron that transferrin can bind (transferrin is the primary protein that binds to iron and transports it throughout the body). These quantities are used to calculate transferrin saturation, an indicator of the body’s iron status. In iron deficiency states, iron levels are low while the TIBC is higher, resulting in low transferrin saturation. In iron overload states, iron levels are high while the TIBC is low or normal, resulting in increased transferrin saturation. 

 

Estradiol

The estradiol (E2) blood test is a test that will check the estradiol, also known as 17 beta-estradiol, level in the blood. The estradiol test is often referred to as the E2 test. Although this is the most commonly ordered fertility test to check estradiol levels in women that have infertility problems and also for in vitro fertilization support, it is also ordered to monitor estradiol levels in fertile females and males.

 

Progesterone

Progesterone is a female hormone produced by the ovaries during ovulation. If an egg is fertilized by sperm, progesterone helps prepare the lining of the uterus (endometrium) to receive the egg. If the egg does not become fertilized, progesterone levels drop and menstrual bleeding begins. The placenta produces high levels of progesterone during pregnancy, beginning at the end of the first trimester and continuing through birth. Pregnant women have progesterone levels almost 10 times higher than non-pregnant women. Additionally, certain types of cancer cause abnormal progesterone levels in both women and men.

 

DHEAs

DHEA sulfate is an androgen (male sex hormone) that is present in the blood of both men and women. It assists in the development of male secondary sexual characteristics at puberty, and can be metabolized into testosterone and androstenedione (more potent androgens), or changed into estrogen (a female hormone). The outer layer of the adrenal glands, the adrenal cortex, is responsible for producing DHEA sulfate, while smaller amounts are produced in the testes and ovaries. 

 

Dehydroepiandrosterone sulfate secretion is controlled by the pituitary hormone adrenocorticotropic hormone (ACTH) and other pituitary factors. Since DHEA,s is primarily produced by the adrenal glands, it is a strong marker for adrenal function. Cancers, adrenal tumors and hyperplasia can lead to the overproduction of DHEA sulfate. While elevated levels may not be noticed in adult men, they can lead to visible symptoms of virilization and amenorrhea.

 

Human Growth Hormone (HGH)

Human growth hormone (HGH)—or simply growth hormone (GH)—is produced by the pituitary gland and secreted into the bloodstream in pulses at various points throughout the day. These pulses range from between 10 and 30 per day, and can be strengthened by exercise. As the name suggests, growth hormone is essential for normal growth and development in children. Although not as active in adults, GH helps regulate bone density, muscle mass and lipid metabolism, and is important for tissue repair, muscle growth, bone strength, brain function, physical and mental health, energy and metabolism.

 

Hemoglobin A1c

The Hemoglobin A1c test is used to evaluate glucose levels in the blood over the last 2 to 3 months. This test is essential in managing one’s diabetes. Researchers believe that keeping the blood sugar in the body within a normal range can help people with diabetes avoid many of the risks and side effects of diabetes. For many people with diabetes, the goal is to keep the level below 7%. Additionally, a significant benefit of the hemoglobin A1c blood test is that it provides information on overall glycemic health over several months. Other blood tests that evaluate glucose levels are highly sensitive to determining glucose levels at the time of collection, but they do not give information on average glucose blood levels.

 

Thyroxine Free (T4) Direct

The free thyroxine (T4) direct serum test helps to evaluate thyroid gland function. The free T4 test is a newer counterpart to the total T4 test and has generally replaced its use. Both are used to help diagnose hyperthyroidism and hypothyroidism. The total T4 test results are affected by the amount of proteins available in the blood to bind the hormone whereas the free T4 test results are not affected by the amount of proteins in the blood. 

 

Tri-Iodothyronine (T3) Free

Free T3 measures the free, unbound levels of triiodothyronine in your bloodstream. Free T3 is considered more accurate than Total T3. Free T3 is typically elevated in hyperthyroidism, and lowered in hypothyroidism. Most of the thyroid hormones circulating in the blood are bound to carrier proteins. This test measures the level of the active thyroid hormone T3 which is free (not bound to protein) and therefore available to your cells to regulate metabolism. Raised levels of FT3 indicate an overactive thyroid whereas low levels indicate that your thyroid is not producing enough thyroid hormones. 

 

Homocysteine

Homocysteine is an amino acid that can be linked to several vitamins like folic acid, B6 and B12. Deficiencies of these vitamins may cause elevated levels of homocysteine. Research suggest that people with elevated homocysteine levels have a much greater risk of heart attack or stroke than those with normal levels. Additionally, increased concentrations of homocysteine have been linked to an increase in blood clots, which can lead to strokes, heart attack and blood vessel blockages in any part of the body.

 

C-Reactive Protein, High Sensitivity

The CRP Blood Test, High Sensitivity, Cardiac Risk Assessment test uncovers lower levels of CRP, a protein that is released into the blood, than the standard CRP test. This test might also be used to evaluate a person's risk for cardiovascular disease. Studies have shown that measuring CRP with a highly sensitive assay can help in exposing the risk level for CVD in healthy people. Normal or mildly elevated amounts of CRP in healthy individuals can help in predicting the future risk of stroke, peripheral arterial disease, sudden cardiac death, heart attack, and even to the point of when cholesterol levels are within the acceptable range.

 

CRP is a marker of inflammation which can affect many organs. Studies have directed their focus on heart disease, but as research develops it is showing that having high CRP levels may also be associated with conditions such as complications of diabetes, obesity, and colon cancer.

 

Vitamin A

Vitamin A, also known as Retinol, is an essential nutrient for healthy skin, healthy eyes and vision, bone growth, immune function, and embryonic development. Vitamin A is present in the liver, dairy products, fish liver oils, dark green and yellow-orange vegetables, and in fruits. Too much vitamin A may cause symptoms that include itchy skin, headache, and hair loss.

 

FSH and LH

The amounts of Luteinizing hormone or LH and Follicle-stimulating Hormone or FSH as well as other hormones (progesterone, and estrogen) are measured in both a man and a woman to determine infertility. The LH and FSH levels may help determine whether male or female sex organs (testicles or ovaries) are properly functioning.

 

Vitamin B12

Vitamin B12 is necessary for the formation of normal red blood cells, nerve function, and tissue and cellular repair. It is not produced in the human body but rather ingested when consuming foods such as red meat, poultry, fish, milk, eggs, and fortified products such as certain breakfast cereals and bread. Deficiencies can be caused by malabsorption (when a disease or other condition interferes with the absorption process) or insufficient dietary intake, although this is unusual in the United States due to the number of food items that have added B12. Vegans and those who do not consume animal products may be more prone to deficiencies.

 

Folate

Folic acid is a B9 vitamin that our bodies uses to make new cells. It is important because it can help prevent major birth defects of the baby's brain and spine (anencephaly and spina bifida) by 50% to 70%. Women need folic acid every day, whether they're planning to get pregnant or not, for the healthy new cells the body makes daily. The amount of folate inside the red blood cell (RBC) is usually at a higher concentration inside the cell than in the serum. Folate may also be ordered to help in diagnosing the cause of behavioral or mental changes, especially in the elderly. Necessary for normal RBC formation, tissue and cellular repair, and DNA synthesis, folate is found in leafy green vegetables, citrus fruits, dry beans and peas, liver, and yeast.

 

NMR LipoProfile

The NMR LipoProfile test is an advanced cardiovascular diagnostic test that uses nuclear magnetic resonance (NMR) spectroscopy to provide rapid, simultaneous and direct measurement of LDL particle number and size of LDL particles, and also direct measurement of HDL and VLDL subclasses. This detailed lipoprotein particle information allows health professionals to make more effective individualized treatment decisions than previously possible based on standard lipid panel testing. The atherosclerotic culprit not LDL cholesterol, but LDL particle number. 

 

Sex Hormone Binding Globulin (SHBG)

Sex Hormone Binding Globulin (SHBG), is a protein produced by the liver. It binds tightly to the hormones, dihydrotestosterone (DHT), testosterone and estradiol (an estrogen), transporting them in the blood in a metabolically inactive form. The amount of SHBG in a patient's blood is affected by sex and age, increased or decreased testosterone or estrogen production. It can also be affected by diseases and conditions such as obesity, liver disease, and hyperthyroidism or hypothyroidism. Adult males test SHBG and testosterone levels to help determine the cause of infertility, decreased sex drive and erectile dysfunction, especially when total testosterone results are found inconsistent with clinical signs.

 

Cortisol

Cortisol, the major adrenal glucocorticoid steroid hormone, is usually under feedback control by pituitary ACTH and the hypothalamus. Causes of low cortisol include pituitary failure or destruction, with resultant loss of ACTH to stimulate the adrenal, and metabolic errors or destruction of the adrenal gland itself (adrenogenital syndromes, tuberculosis, histoplasmosis). The diagnosis of hypoadrenalism usually requires confirmation with ACTH stimulation, due to the circadian rhythms of cortisol and other factors. Causes of increased cortisol, which may initially present as simply a loss of normal diurnal variation, include pituitary overproduction of ACTH, production of ACTH by a tumor (notably oat cell cancers), and adrenal adenomas.

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