Quick Facts
- Sample: Blood draw and urine collection
- Fasting: Not required
- Turn-around: 3-5 business days. May take longer based on weather, holiday, or lab delays.
Benefits
- Comprehensive aging assessment - 40+ biomarkers across 17 tests evaluate hormones, growth factors, and metabolic health
- Early detection advantage - Identify age-related changes before symptoms appear for proactive intervention
- Hormone optimization insights - Precise measurements of DHEA-S, estradiol, testosterone, and progesterone levels
- Growth factor analysis - IGF-1 and growth hormone testing reveals biological aging patterns
- No physician referral needed - Direct access to advanced anti-aging testing with confidential results
- Cost-effective monitoring - Significant savings compared to traditional healthcare settings
Who Is This Test For?
- Women aged 35-65 experiencing unexplained fatigue, mood changes, or sleep disturbances
- Those in perimenopause or menopause transition seeking hormone level assessment
- Health-conscious women wanting baseline biomarker establishment for aging monitoring
- Individuals considering hormone replacement therapy requiring pre-treatment evaluation
- Women with family history of early menopause or age-related health conditions
- Anyone seeking proactive health insights without traditional physician referrals
How It Works – Just 3 Steps
- Order your test - Visit any nearby lab location for blood draw and urine collection
- Get tested - Quick blood collection via standard venipuncture; provide first-morning urine sample
- Review results - Receive comprehensive biomarker analysis with reference ranges via secure online portal
FAQ
What hormones does this panel measure? The panel evaluates horomones (DHEA-S, estradiol, progesterone, total and free testosterone, growth hormone), thyroid function, lipid panel, comprehensive metabolic panel, Phosphate (as Phosphorus), uric acid, LD, GGT, CBC w/ diff, Urinalysis, Complete, iron total and TIBC, vitamin D, and IGF-1.
Do I need to fast before testing? No fasting is required. Avoid biotin supplements 72 hours before testing for accurate results.
How often should I repeat this test? Consider retesting every 12-24 months to monitor trends, or as recommended by your healthcare provider.
Can this test diagnose menopause? This panel provides valuable hormone insights, but menopause diagnosis requires clinical evaluation by a healthcare provider.
What if my results are abnormal? Consult with a healthcare provider for proper interpretation and personalized treatment recommendations based on your results.
More Details
What is the purpose of this test?
This comprehensive panel evaluates key aging biomarkers including hormones (estradiol, testosterone, DHEA-S), growth factors (IGF-1, growth hormone), and metabolic markers to assess biological aging and identify hormone-related changes in women (PMC/National Library of Medicine 2024). The testing approach provides insights into hormonal balance, metabolic function, and overall physiological aging patterns, enabling proactive health management and early detection of age-related changes.
Research demonstrates that bioavailable testosterone, DHEA-S, and IGF-1/GH ratio show highly significant negative correlations with age and serve as valuable aging biomarkers (Mayo Clinic 2019). With six thousand women entering menopause daily in the United States and up to 85% experiencing menopause-related symptoms, this testing provides valuable insights for informed healthcare decisions (RupaHealth 2024).
Who would benefit from this test?
Women aged 35-65 experiencing symptoms like fatigue, mood changes, sleep disturbances, or irregular periods would benefit most from this comprehensive assessment. The panel is particularly valuable for women in perimenopause or menopause transition, as approximately 20-40% of women experience PMS symptoms, 8% experience PMDD, and 6-12% have PCOS (RupaHealth 2024).
Those seeking proactive health monitoring, considering hormone replacement therapy, or wanting baseline establishment before significant hormonal changes occur will find this testing especially beneficial. The panel also serves women with family history of early menopause or those experiencing unexplained symptoms that may be hormone-related.
When should I order this panel?
Consider testing if experiencing unexplained fatigue, mood swings, irregular periods, decreased energy, or changes in sleep patterns. Baseline assessment is recommended before age 40, with repeat testing every 1-2 years or as recommended by your healthcare provider (PMC 2022).
For women still menstruating, note your menstrual cycle day for optimal hormone interpretation. Those considering hormone replacement therapy should establish baseline levels before beginning treatment (Mayo Clinic 2024).
How do I interpret the results?
Results show individual biomarker levels compared to age-appropriate reference ranges. Hormone levels naturally decline with age, requiring professional interpretation for personalized recommendations.
DHEA-S
- Normal Range (Women):
- 1.12–7.43 ng/mL (pre-menopause)
- 0.6–5.7 ng/mL (post-menopause)
- Age-Related Changes: Declines to 10–20% of youthful levels by age 70–80
Testosterone
- Normal Range (Women): 0.5–1.1 ng/mL
- Age-Related Changes: Gradual decline with age and menopause
Estradiol
- Normal Range (Women): Varies by cycle phase/menopause status
- Age-Related Changes: Significant decline during perimenopause
IGF-1
- Normal Range (Women): Age-specific reference ranges
- Age-Related Changes: Strong negative correlation with aging
Research shows high negative correlations with age (r > -0.6) for bioavailable testosterone, DHEA-S, and IGF-1/GH ratio, establishing these as reliable aging indicators (PNAS 1997).
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
Pre-test preparation
No fasting is required for this comprehensive panel. Discontinue biotin supplements 72 hours before testing to ensure accurate results. If you're still menstruating, note your cycle day for proper hormone interpretation.
Stay well-hydrated for easier blood collection and avoid strenuous exercise 24 hours before testing. Collect the first-morning midstream urine specimen in the provided sterile container for optimal urinalysis results.
How often should I get tested?
- Baseline establishment (age 35–40): Once, then every 2–3 years
- Perimenopause symptoms: Every 12–18 months
- Hormone replacement therapy monitoring: Every 6–12 months
- Post-menopause wellness tracking: Every 1–2 years
- Abnormal previous results: As recommended by provider
Why early detection matters
Age-related chronic diseases account for over 90% of annual healthcare expenditures (more than $4.1 trillion) in the US alone, emphasizing the value of early detection and preventive intervention through biomarker testing (Nature Publishing 2024).
Menopausal hormone therapy use declined dramatically from 26.9% to just 4.7% from 1999 to 2020, indicating significant underutilization despite proven effectiveness (JAMA Health Forum 2024). Early detection through comprehensive biomarker testing enables timely intervention and improved quality of life outcomes.
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