Quick Facts
- Sample: Blood
- Fasting: You should maintain a stable diet for 2 to 3 weeks and fast for 14 to 16 hours before your blood collection. Stop biotin supplements at least 72 hours prior, and avoid exercise before the test.
- Turnaround: 3-4 business days. This may take longer due to weather, holidays, or lab delays.
What's Included
C-Reactive Protein (CRP)
C-Reactive Protein (CRP): A protein produced by the liver in response to inflammation, infection, or tissue injury. Helps detect and monitor inflammatory activity, evaluate certain infections and autoimmune conditions, and assess response to treatment.
Rheumatoid Factor (RF)
Rheumatoid Factor (RF): An autoantibody that targets other antibodies in the immune system and is commonly associated with rheumatoid arthritis. Helps evaluate rheumatoid arthritis and other autoimmune conditions, including Sjögren's syndrome, when interpreted alongside symptoms and other laboratory findings.
Antinuclear Antibodies (ANA)
Important: The ANA test included in this panel varies by laboratory. The LabCorp version includes the Antinuclear Antibodies (ANA) Direct Blood Test, Qualitative, while the Quest Diagnostics version includes the ANA Screen, IFA, with Reflex to Titer and Pattern Blood Test. Both tests evaluate antinuclear antibodies for autoimmune disease assessment but use different methods and may differ in reflex testing and result reporting. Results should be interpreted along with your symptoms, medical history, and other laboratory findings.
Erythrocyte Sedimentation Rate (ESR)
Erythrocyte Sedimentation Rate (ESR): A blood test that measures how quickly red blood cells settle in a sample over a specified period. Helps detect and monitor inflammation associated with autoimmune diseases, infections, and certain cancers, although elevated levels do not identify a specific condition.
Cyclic Citrullinated Peptide (CCP) Antibodies, IgG/IgA
Cyclic Citrullinated Peptide (CCP) Antibodies, IgG/IgA: Autoantibodies that target citrullinated proteins and are commonly associated with rheumatoid arthritis. Helps support the diagnosis of rheumatoid arthritis, particularly when evaluated alongside symptoms, physical examination findings, and other laboratory tests.
Complement C3
Complement C3: A protein involved in the complement system, a part of the immune system that helps fight infections and clear damaged cells. Helps evaluate immune system activity, investigate certain complement deficiencies, and monitor autoimmune conditions such as lupus.
Creatine Kinase (CPK)
Creatine Kinase (CPK): An enzyme found primarily in skeletal muscles, the heart, and the brain that helps produce and store energy for muscle activity. Elevated levels may indicate muscle damage, inflammation, or injury and help evaluate certain muscle disorders.
Aldolase
Aldolase: An enzyme found in muscle and other tissues that helps break down glucose for energy production. Elevated levels may indicate muscle damage or inflammation and help evaluate muscle disorders, including inflammatory myopathies, and monitor response to treatment.
Comprehensive Metabolic Panel (CMP-14)
Blood Sugar
Kidney Profile
- BUN (Blood Urea Nitrogen): A waste product formed when the body breaks down protein, normally removed by the kidneys.
- Creatinine, Serum: A waste product from normal muscle activity that is filtered from the blood by the kidneys.
- BUN/Creatinine Ratio: A calculated value (BUN divided by creatinine) that can suggest conditions like dehydration or intestinal bleeding.
- Estimated Glomerular Filtration Rate (eGFR): A calculated estimate of how effectively the kidneys filter waste from the blood, used to assess kidney function.
Liver Panel
- Protein, Total: The combined amount of albumin and globulin proteins in the blood, which helps assess liver and kidney function and nutritional health.
- Albumin, Serum: A protein produced by the liver that helps maintain fluid balance and transport substances through the blood.
- Globulin, Total: A group of blood proteins involved in immune defense, transporting substances, and other important body functions.
- Albumin/Globulin Ratio: A calculated value (albumin divided by globulin) that, alongside other results, can assist in evaluating liver problems.
- Bilirubin, Total: A yellow pigment produced during the normal breakdown of red blood cells and processed by the liver. Elevated levels can cause jaundice.
- Alkaline Phosphatase: An enzyme found primarily in the liver, bile ducts, and bones that can help identify liver or bone disorders.
- Aspartate Aminotransferase (AST or SGOT): An enzyme found in the liver and other tissues, such as the heart and muscles, that is released into the blood when cells are damaged.
- Alanine Aminotransferase (ALT or SGPT): An enzyme that helps identify liver damage. Abnormal levels may represent liver disease.
Fluids & Electrolytes
- Sodium: One of the major salts in your body fluid, important for water balance and the electrical activity of nerves and muscles.
- Potassium: Helps control the function of your nerves and muscles.
- Chloride: Similar to sodium, it helps maintain your body's electrolyte balance.
- Carbon Dioxide, Total: A measure that primarily reflects bicarbonate in the blood, helping assess the body's acid-base balance.
- Calcium: A mineral essential for developing and maintaining healthy bones and teeth, and for normal muscle, nerve, and blood clotting function.
Lipid Panel Blood Test with Total Cholesterol: HDL Ratio
- Cholesterol, Total: A measurement used to assess heart health. Cholesterol is required by your body to build healthy cells, but high cholesterol levels can increase your risk of heart disease.
- Triglycerides: Surplus fats transported in the bloodstream and provide energy to the body.
- HDL Cholesterol: High-density lipoproteins, or "good" cholesterol, take cholesterol away from the cells and transport it back to the liver for removal or processing.
- LDL Cholesterol: Low-density lipoproteins (calculation), or "bad" cholesterol, contain the highest percentage of cholesterol and are responsible for depositing cholesterol on the artery walls.
- Non HDL Cholesterol (Not Included with LabCorp): A measure of cholesterol carried outside of HDL particles.
- Total Cholesterol: HDL Ratio: The Total Cholesterol to HDL Ratio is a critical indicator of the balance between good and bad cholesterol in the body. A ratio of less than 5:1 is considered optimal, while a ratio higher than 6:1 indicates an increased risk of developing heart disease.
Thyroid Panel with TSH
- TSH (Thyroid Stimulating Hormone): Produced by the pituitary gland, this hormone helps the thyroid create T4 and T3.
- T4 (Thyroxine), Total: A hormone made by the thyroid that helps maintain metabolism and other body functions.
- T3 Uptake: Evaluates the number of blood proteins that carry thyroid hormones throughout the body.
- Free T4 Index (T7): A calculated value comparing the amount of unbound (free) T4 to T4 bound to proteins in the blood.
Complete Blood Count (CBC) with Differential and Platelets Blood Test
White Blood Cells
Red Blood Cells and Red Cell Indices
- Red Blood Cells (RBC): Carries oxygen and carbon dioxide to and from your cells. Iron deficiency can lower this count.
- Hemoglobin: A compound inside red cells that carries oxygen through your bloodstream and gives blood its red color.
- Hematocrit: The percentage of blood volume made up of red blood cells.
- MCH (Mean Corpuscular Hemoglobin): The average hemoglobin amount within a single red blood cell.
- MCHC (Mean Corpuscular Hemoglobin Concentration): The average hemoglobin concentration percentage within a red blood cell.
- MCV (Mean Corpuscular Volume): The average size of your red blood cells.
- RDW (Red Cell Distribution Width): Measures the variation in volume and size among your red blood cells.
Platelets
- Platelet Count: Blood cell particles that play a role in forming blood clots.
- MPV (Mean Platelet Volume): The average size of platelets in the blood, providing information about platelet production and activity.
White Blood Cell Differential
- Neutrophils: The most common white blood cell type, created by your bone marrow to combat inflammatory and infectious conditions.
- Lymphocytes: B cells and T cells that fight bacteria and other pathogens, found mainly in your lymph system.
- Monocytes: Work alongside neutrophils to fight infections and clear away dead or damaged cells.
- Eos (Eosinophils): White blood cells that become active in response to allergies and certain infections.
- Basophils: Help detect infections early, support wound healing, and respond to allergic reactions.
- Immature Granulocytes: A component of your white blood cell differential included in this panel. (Labcorp only)
Gamma-Glutamyl Transferase (GGT)
Gamma-Glutamyl Transferase (GGT): An enzyme found mainly in the liver and bile ducts that helps metabolize certain substances. Elevated levels may indicate liver damage, bile duct disorders, or other conditions affecting liver function.
Iron, Total
Iron, Total: The concentration of iron circulating in the blood, primarily bound to transferrin. Helps assess iron availability for hemoglobin production and evaluate iron deficiency, anemia, and iron overload.
Uric Acid
Phosphorus
Phosphorus: A mineral essential for bone and tooth formation, energy production, and normal muscle and nerve function. Helps evaluate kidney function, bone health, and mineral balance.
Lactate Dehydrogenase (LDH)
Lactate Dehydrogenase (LDH): An enzyme found in many tissues, including the liver, heart, muscles, kidneys, and blood cells, that helps convert sugars into energy.
Benefits
- Screens for rheumatoid arthritis and related autoimmune activity.
- Supports monitoring of disease severity over time.
- Helps track your response to ongoing treatment.
- Helps detect potential treatment-related side effects.
- Pairs autoimmune markers with a broad wellness panel.
- Covers metabolic, lipid, thyroid, and blood cell health in one draw.
Who Is This Test For?
- Individuals wanting to screen for rheumatoid arthritis or autoimmune activity.
- Those currently monitoring an existing autoimmune or inflammatory condition.
- People wanting to track their response to ongoing treatment.
- Individuals wanting a broad wellness check alongside autoimmune screening.
- Those working with a healthcare provider to follow disease activity over time.
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. What is the purpose of this test?
This panel combines rheumatoid arthritis and autoimmune markers—including CRP, rheumatoid factor, ANA, ESR, CCP antibodies, complement C3, creatine kinase, and aldolase—with the Wellness #2 Essential Panel. Together, these tests help screen for rheumatoid arthritis and autoimmune disease activity while also reviewing metabolic, lipid, thyroid, and blood cell health. This panel does not diagnose any condition on its own.
2. Who may benefit from this test, and when should it be ordered?
This panel may benefit individuals who want to screen for rheumatoid arthritis or autoimmune activity, as well as those already managing a related condition. You might consider ordering it for general screening, ongoing monitoring of an autoimmune or inflammatory condition, or follow-up after beginning or adjusting a treatment plan. It may also suit those seeking a broader view of their overall wellness alongside these markers.
3. How should I prepare for this test?
Maintain a stable diet for 2 to 3 weeks and fast for 14 to 16 hours before your blood collection. Stop taking biotin supplements at least 72 hours beforehand and avoid exercise before the test.
4. How quickly will I receive my results?
Results are typically available within 3 to 4 business days. However, weather, holidays, or laboratory delays may extend the turnaround time.
5. How should I interpret my results?
Results are best understood as patterns across multiple biomarkers rather than as individual values viewed in isolation. Changes across related autoimmune and inflammatory markers may be more meaningful when considered together. Discuss your complete results with your healthcare provider, who can interpret them in the context of your health history.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
6. What should I do if a result is outside the expected range?
Share the result with your healthcare provider. They can explain what it may mean for you and determine whether follow-up testing or care is needed.
7. How often should I get tested?
Testing frequency depends on your individual health circumstances and any conditions you may be monitoring. Reviewing autoimmune and inflammatory markers alongside a broader wellness panel may support earlier awareness of changes and ongoing monitoring over time. Follow your healthcare provider’s recommendations to determine an appropriate testing schedule.
Pre-test preparation
You should maintain a stable diet for 2 to 3 weeks and fast for 14 to 16 hours before your blood collection. Stop biotin supplements at least 72 hours prior, and avoid exercise before the test. Do not stop prescribed medication unless instructed by your healthcare provider.
