Quick Facts
- Sample: Blood sample from a vein
- Fasting: Fasting for 10-12 hours is required. Stop DHEA supplements and biotin 72 hours before testing.
- Turnaround: 6-7 business days. May take longer based on weather, holiday, or lab delays.
What This Test Measures
This test measures dehydroepiandrosterone (DHEA), also called unconjugated DHEA, in the blood using liquid chromatography-tandem mass spectrometry (LC-MS/MS). DHEA is a steroid hormone produced primarily by the adrenal glands, with additional production by the gonads.
DHEA serves as a precursor that the body can use in the production of other steroid hormones. DHEA levels generally increase before puberty and decline with age. Measuring DHEA can provide information that may be considered when evaluating adrenal hormone production and certain conditions associated with abnormal DHEA levels.
This test measures DHEA itself and should not be confused with a DHEA-Sulfate (DHEA-S) test, which measures the sulfated form of the hormone.
Benefits
- Measures circulating DHEA using LC-MS/MS methodology
- Helps evaluate adrenal hormone production
- Supports assessment of abnormal DHEA levels
- Provides a specific measurement of unconjugated DHEA
- Offers a laboratory value that can be reviewed with a healthcare provider
Who Is This Test For?
- Individuals undergoing evaluation of DHEA levels for adrenal-related concerns
- Individuals undergoing evaluation of DHEA levels for androgen-related concerns
- Individuals with symptoms that may be associated with abnormal adrenal hormone production
- Individuals with laboratory findings that may indicate abnormal adrenal hormone production
- Individuals having DHEA measured alongside other hormone tests as part of a broader hormonal evaluation
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. What does this test measure?
This test measures dehydroepiandrosterone (DHEA), also known as unconjugated DHEA, in the blood. DHEA is a steroid hormone produced primarily by the adrenal glands and serves as a precursor in the production of other steroid hormones.
2. Is DHEA the same as DHEA-S?
No. DHEA and DHEA-Sulfate (DHEA-S) are related but distinct forms. This test measures unconjugated DHEA rather than DHEA-S. If you need DHEA-S measurement, a DHEA-Sulfate test should be ordered instead.
3. Do I need to fast before testing?
Yes, you will need to fast for 10-12 hours before collection.
4. What testing method is used?
DHEA is measured using liquid chromatography-tandem mass spectrometry (LC-MS/MS), an analytical method used for steroid hormone measurement.
5. How do I interpret my results?
DHEA results should be interpreted using the reference interval supplied by the laboratory that performed your test. Expected levels vary with factors such as age and sex.
A result outside the laboratory's reference interval does not diagnose a medical condition on its own. Review abnormal results with a qualified healthcare provider, who can consider your result together with your symptoms, medical history, medications, supplements, and other laboratory findings.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
6. What should I do if my result is abnormal?
Discuss the result with a qualified healthcare provider. Depending on your symptoms, medical history, and other laboratory findings, your provider can determine whether additional evaluation or testing is appropriate.
7. How often should I get tested?
There is no universal testing schedule for DHEA. Testing frequency depends on the reason for testing and should be determined with your healthcare provider.
Pre-test Preparation
Fasting for 10-12 hours is required. Stop DHEA supplements and biotin 72 hours before testing.
