Quick Facts
- Sample: Saliva
- Fasting: No fasting required
- Turn-around: 5-7 business days once the lab receives the specimen. May take longer based on weather, holiday, or lab delays.
Benefits
- Monitor bioavailable hormones - Saliva testing reflects active hormone levels your body can actually use
- Convenient at-home collection - Simple morning saliva sample with no clinic visit required
- Highly accurate results - LC-MS/MS technology provides 98% specificity and 97% sensitivity
- Comprehensive hormone profile - Tests three key hormones affecting mood, energy, and reproductive health
- Confidential health insights - Private results access
- Proactive wellness monitoring - Early detection helps prevent symptoms and guide treatment decisions
Who Is This Test For?
- Women experiencing menopause symptoms like hot flashes, mood swings, or irregular periods
- Adults with unexplained fatigue or persistent low energy levels
- Individuals with fertility concerns or reproductive health challenges
- People considering hormone therapy who need baseline measurements or monitoring
- Men with low libido or suspected testosterone imbalance
- Anyone seeking preventive health insights into their hormonal wellness
How It Works – Just 3 Steps
- Order online - No doctor's order required; kit ships directly to you
- Collect saliva sample - Simple morning collection in provided tube, then freeze if not shipping within 24 hours
- Get results - Lab analyzes sample and delivers results online within 5-7 business days
FAQ
What hormones does this test measure? This test measures estradiol (E2), progesterone (Pg), and testosterone (T) - three key hormones that regulate mood, energy, and reproductive function.
Is saliva testing as accurate as blood testing? Yes, saliva testing using validated LC-MS/MS methods accurately reflects bioavailable steroid hormones with 98% specificity (Mayo Clinic 2022).
When should I collect my sample? Collect your saliva sample first thing in the morning upon waking, before eating, drinking, or brushing your teeth.
Do I need to fast before this test? No fasting is required, but avoid eating, drinking (except water), or brushing teeth for 2 hours before collection.
Can men use this test too? Yes, this test is designed for both men and women to assess hormone balance and related symptoms.
How often should I retest? Retest every 3-6 months if monitoring hormone therapy or significant symptoms, or annually for general wellness screening.
More Details
What is the purpose of this test?
The Hormone Trio Saliva Test measures levels of estradiol, progesterone, and testosterone in your saliva to provide insights into your hormone balance. These three hormones play crucial roles in regulating mood, energy levels, sexual function, and reproductive health for both men and women. By measuring bioavailable hormone levels through saliva, this test helps identify imbalances that may be causing symptoms like fatigue, mood swings, low libido, or irregular menstrual cycles.
Who would benefit from this test?
This test is particularly valuable for adults experiencing symptoms of hormone imbalance, including women going through menopause or perimenopause, men with suspected low testosterone, individuals with fertility challenges, and anyone considering or currently on hormone replacement therapy. It's also beneficial for people experiencing unexplained fatigue, mood changes, sexual dysfunction, or menstrual irregularities who want to understand if hormones are contributing to their symptoms.
When should I order Hormone Trio Saliva - ZRT Test Kit?
Consider ordering this test if you have persistent symptoms suggestive of hormone imbalance, are beginning or changing hormone therapy, or want a baseline assessment for preventive health monitoring. For menstruating women, timing the collection according to your cycle (as instructed in the kit) provides the most accurate results. The test is also recommended before starting any hormone supplementation program.
How do I interpret the results?
Your results will show your hormone levels compared to age- and sex-specific reference ranges. Consult with a healthcare professional for abnormal results or guidance on next steps.
Within normal range
- What it means: Balanced hormone levels
- Typical action: Continue healthy lifestyle habits
Below normal range
- What it means: Potential hormone deficiency
- Typical action: Consult healthcare provider about supplementation
Above normal range
- What it means: Possible hormone excess
- Typical action: Evaluate medications, supplements, or underlying conditions
Early identification and treatment of hormone imbalances can reduce related healthcare costs by up to 30% and significantly improve quality of life (Endocrine Society 2023).
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
Pre-test preparation
No fasting is required for this test. Collect your saliva sample first thing in the morning upon waking. Avoid anti-aging creams containing hormones for 3 days before testing, and do not eat, drink (except water), or brush your teeth for 2 hours before sample collection. For menstruating women, follow the cycle timing instructions provided in your test kit for optimal accuracy.
How often should I get tested?
- Monitoring hormone therapy: Every 3–6 months
- Significant symptoms present: Every 3–6 months
- General wellness screening: Annually
- Post-treatment follow-up: As recommended by healthcare provider
Why early detection matters
Approximately 47 million U.S. women enter menopause each year, with up to 80% experiencing symptomatic hormone fluctuations (CDC 2023). PCOS affects 1 in 10 women of reproductive age, making hormonal imbalance a leading cause of infertility. Early identification of hormone imbalances allows for timely intervention through lifestyle modifications, targeted supplementation, or hormone replacement therapy, potentially preventing more serious health complications and improving overall quality of life.
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