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Vitamin D 1,25 Dihydroxy (Calcitriol) Blood Test

The Vitamin D 1,25 Dihydroxy (Calcitriol) Blood Test measures the vitamin D levels in the blood to assist with differential diagnosis of hypocalcemia and to monitor bone disease or chronic kidney failure treatment. 


Test Code: 081091

CPT Code: 82652

Also Known As: 1,25(OH) Vitamin D, 1,25-Dihydroxy Vitamin D, 1,25-Dihydroxycholecalciferol, Vitamin D, 1,25-Dihydroxy

Methodology:

Immunochemiluminometric assay (ICMA)

Preparation:

No special preparation required.

Test Results:

3-4 days. May take longer based on weather, holiday or lab delays.

Sample Report

Test Code: 16558

CPT Code: 82652

Also Known As: 1,25(OH) Vitamin D, 1,25-Dihydroxy Vitamin D, 1,25-Dihydroxycholecalciferol, Vitamin D, 1,25-Dihydroxy

Methodology:

Chromatography/Mass Spectrometry

Preparation:

No special preparation required.

Test Results:

3-4 days. May take longer based on weather, holiday or lab delays.


Details:

This test includes the following:

  • Vitamin D,1,25 (OH)2,Total
  • Vitamin D3, 1,25 (OH)2
  • Vitamin D2, 1,25 (OH)2

Description

Order this Vitamin D 1,25 Dihydroxy Blood Test to measure the active form of vitamin D to assist with differential diagnosis of hypocalcemia and to monitor patients with a bone disease or chronic kidney failure. Vitamin D 1,25-Dihydroxy, also known as Calcitriol, is produced in the liver and kidneys by converting Vitamin D 25-Hydroxy. Calcitriol is also a form of vitamin D used to treat and prevent low calcium levels in the blood of patients with dysfunctional kidneys or parathyroid glands.

A low level of 1,25-dihydroxyvitamin D can be seen in acute kidney disease, as it is one of the earliest changes to occur in individuals with early-stage kidney failure. In addition, low levels of 1,25-dihydroxyvitamin D can be detected in individuals with hypoparathyroidism. However, a high level of 1,25-dihydroxyvitamin D may occur in sarcoidosis or some lymphomas, malignancies, primary hyperparathyroidism, and physiologic hyperparathyroidism.

This test is not recommended as a routine measurement to assess if a person has a vitamin D deficiency. Normal results may be indicated even if an individual has an overall deficiency. Therefore, this test is unsuitable for diagnosing vitamin D deficiency and monitoring supplementation in most patients. The Vitamin D 25-Hydroxy Blood Test is the recommended test for those purposes.

Individuals may also order this test to assist in diagnosing the following conditions:

  • Parathyroid disorder
  • Kidney failure
  • Primary hyperparathyroidism
  • Hypoparathyroidism
  • Pseudohypoparathyroidism
  • Renal osteodystrophy
  • Vitamin d-resistant rickets

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