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The NMR LipoProfile #3 Extreme Blood Test Panel

The NMR LipoProfile, Homoecysteine, C-Reactive Protein Cardiac plus Comprehensive Metabolic Profile - 14 tests, Lipid Profile, Hemoglobin A1c.


Test Code: 2312

CPT Code: See Individual Tests

Also Known As:

Methodology:

See Individual Tests

Specimen Type: Blood

Preparation:

Patient should be on a stable diet, ideally for two to three weeks prior to collection of blood, and should fast for 12 to 14 hours before collection of the specimen.

Test Results:

4-6 days. May take longer based on weather, holiday or lab delays.

Description

The NMR LipoProfile test is an advanced cardiovascular diagnostic test that uses nuclear magnetic resonance (NMR) spectroscopy to provide rapid, simultaneous and direct measurement of LDL particle number and size of LDL particles, and also direct measurement of HDL and VLDL subclasses.  This detailed lipoprotein particle information allows health professionals to make more effective individualized treatment decisions than previously possible based on standard lipid panel testing. The atherosclerotic culprit not LDL cholesterol, but LDL particle number. 

Homocysteine is an amino acid found normally in the body. Its metabolism is linked to that of several vitamins, especially folic acid, B6, and B12, and deficiencies of those vitamins may cause elevated levels of homocysteine. Recent studies suggest that those people who have elevated homocysteine levels have a much greater risk of heart attack or stroke than those people with average levels. Increased concentrations of homocysteine have been associated with an increased tendency to form inappropriate blood clots. This can lead to heart attack, strokes, and blood vessel blockages.

CRP,hs test (highly sensitive) can detect lower concentrations of the protein (it is more sensitive), which makes it useful in predicting a healthy person's risk for cardiovascular disease. hs-CRP can play a role in the evaluation process before one encounters one of these health problems. Since the hs-CRP and the standard CRP tests measure the same molecule, people with chronic inflammation, such as arthritis, should not have hs-CRP levels measured. Their CRP levels will be extremely high due to the arthritisoften too high to be measured using the hs-CRP test.

Cholesterol, HDL (the "good" cholesterol), LDL (the "bad" cholesterol), VLDL, Triglycerides, and the Ratio of Good cholesterol to total. The lipid profile is used to help determine heart disease risk and helps guide you and your health care provider in deciding what treatment may be best for you if you have borderline or high risk. The results of the lipid profile are considered along with other risk factors of heart disease to develop a plan of treatment and follow-up. Depending on results and other risk factors, treatment options may involve changes in diet and exercise or lipid-lowering medications such as statins.

The A1c (Glycohemoglobin) test evaluates the average amount of glucose in the blood over the last 2 to 3 months. This is done by measuring the concentration of glycated (also often called glycosylated) hemoglobin A1c. Hemoglobin is an oxygen-transporting protein that is found inside red blood cells (RBCs). There are several types of normal hemoglobin and many identified hemoglobin variants, but the predominant form is hemoglobin A at about 95-98%.

CMP-14 Includes:
Glucose-Blood sugar level, the most direct test to diagnose diabetes, may be used not only to identify diabetes, but also to evaluate how one controls the disease.
Kidney Profile
Bun or Urea Nitrogen A by-product of protein metabolism eliminated through the kidneys, BUN is an indicator of kidney function. 
Creatinine, Serum  Indicates kidney function. 
Bun/Creatinine Ratio
Calculated by dividing the BUN by the Creatinine.
Glomerular Filtration (eGFR) Provides an assessment of the kidney's filtering capacity.
Fluids & Electrolytes
Sodium Sodium is important in the body's water balance and the electrical activity of nerves and muscles and one of the major salts in body fluid.
Potassium Helps to control the muscles and nerves.
Chloride Similar to sodium, chloride helps to maintain the body's electrolyte balance.
Carbon Dioxide, Total Used in detecting, evaluating, and monitoring electrolyte imbalances.
Calcium- A mineral essential for development and maintenance of healthy teeth and bones. It is important also for the normal function of nerves, muscles and blood clotting.
Liver panel
Protein, Total A measure of the state of nutrition in the body together with albumin.
Albumin Serum a major protein in the blood and a reflection of the general state of nutrition. 
Globulin, Total A major group of proteins in the blood that comprise the infection fighting antibodies.
Albumin/Globulin Ratio Calculated by dividing the albumin by the globulin.
Bilirubin, Total A chemical that is involved with liver functions. High concentrations of bilirubin may result in jaundice.
Alkaline Phosphatase A body protein that is important in diagnosing proper bone and liver functions.
Aspartate Aminotransferase (AST or SGOT)an enzyme that is found in skeletal and heart muscle, liver and other organs. Abnormalities may represent liver disease.
Alanine Aminotransferase (ALT or SGPT) an enzyme that is found primarily in the liver. Abnormalities may represent liver disease.

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