Quick Facts
- Sample: Blood and urine
- Fasting: 12 hours required
- Turn-around: 4-5 business days. May take longer based on weather, holiday, or lab delays.
Benefits
- Direct access testing - Skip referrals and get answers quickly
- Comprehensive screening - Rules out conditions with similar symptoms
- Confidential process - Secure, private testing and results
- Treatment guidance - Helps develop personalized management strategies
- Progress monitoring - Track biomarkers over time for treatment effectiveness
Who Is This Test For?
- People experiencing unexplained widespread pain and chronic fatigue
- Individuals with "fibro fog" or cognitive difficulties
- Those seeking to rule out autoimmune or thyroid conditions
- Patients with sleep disturbances and muscle tenderness
- Anyone wanting proactive investigation of persistent symptoms
- People monitoring fibromyalgia treatment response
How It Works – Just 3 Steps
- Order online - Purchase your test kit without a doctor's referral
- Visit a lab - Get your blood and urine samples collected at a nearby location
- Receive results - Get results in 4-5 business days
FAQ
What conditions does this panel help rule out? Autoimmune diseases, thyroid disorders, vitamin deficiencies, anemia, and inflammatory conditions that mimic fibromyalgia symptoms.
Can this test definitively diagnose fibromyalgia? No single blood test confirms fibromyalgia. This panel supports differential diagnosis by identifying or excluding other potential causes of your symptoms.
How accurate are fibromyalgia blood markers? Novel FM/a blood tests report 93% sensitivity and 89% specificity in studies, though fibromyalgia remains primarily a clinical diagnosis (Frontiers in Neurology 2023).
Do I need to stop medications before testing? Stop biotin supplements 72 hours before testing. Avoid starting B12 therapy before the test. Consult your doctor about other medications.
What if my results are normal? Normal results help rule out other conditions but don't exclude fibromyalgia, which is diagnosed based on symptoms and physical examination.
How long does fibromyalgia typically take to diagnose? The average time to fibromyalgia diagnosis exceeds 2 years, with up to 95% of cases initially missed or misdiagnosed (Arthritis Foundation 2022).
More Details
What is the purpose of this test?
The Fibromyalgia Blood Test Panel helps healthcare providers investigate chronic widespread pain, fatigue, and related symptoms by measuring specific blood and urine markers. While no single test can definitively diagnose fibromyalgia, this comprehensive panel supports differential diagnosis by identifying or ruling out conditions with overlapping symptoms (Mayo Clinic 2025).
The panel includes complete blood count, metabolic markers, inflammation indicators, autoimmune screens, and vitamin assessments to provide a thorough evaluation of potential underlying causes.
Who would benefit from this test?
This test benefits people experiencing unexplained chronic pain, persistent fatigue, or cognitive difficulties often called "fibro fog." It's particularly valuable for those whose symptoms have persisted despite initial medical evaluations.
Individuals seeking answers without traditional referral delays can use this panel to proactively investigate their symptoms. Healthcare providers also use these results to guide treatment decisions and monitor therapeutic progress over time.
When should I order Fibromyalgia Blood Test Panel?
Order this panel when you experience persistent widespread pain lasting more than three months, accompanied by fatigue, sleep disturbances, or cognitive issues. It's especially useful when initial medical evaluations haven't provided clear answers.
Consider testing if you have tender points throughout your body, morning stiffness, or symptoms that worsen with stress or weather changes. The panel is also valuable for monitoring existing fibromyalgia treatment effectiveness.
How do I interpret the results?
Results should be reviewed with a qualified healthcare provider who can interpret findings within the context of your symptoms and medical history. The panel helps identify specific abnormalities that might explain your symptoms or supports a fibromyalgia diagnosis when other conditions are ruled out.
CBC (Complete Blood Count)
- Purpose: Rule out anemia/infection
- Abnormal results may indicate: Fatigue from blood disorders
CMP (Comprehensive Metabolic Panel)
- Purpose: Check organ function
- Abnormal results may indicate: Liver/kidney issues causing symptoms
CRP/ESR (C-Reactive Protein / Erythrocyte Sedimentation Rate)
- Purpose: Measure inflammation
- Abnormal results may indicate: Inflammatory conditions
ANA (Antinuclear Antibody Test)
- Purpose: Screen for autoimmune disease
- Abnormal results may indicate: Lupus, Sjögren's, or similar conditions
Thyroid (TSH - Thyroid Stimulating Hormone)
- Purpose: Assess thyroid function
- Abnormal results may indicate: Hypothyroidism mimicking fibromyalgia
Vitamins D/B12
- Purpose: Check for deficiencies
- Abnormal results may indicate: Nutritional causes of symptoms
Fibromyalgia affects an estimated 2-4% of people worldwide, predominantly women, making comprehensive screening essential for accurate diagnosis.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
Pre-test preparation
Fast for at least 12 hours before your blood draw, avoiding all food and beverages except water. Stop taking biotin supplements at least 72 hours before testing to prevent interference with certain assays.
Avoid vigorous exercise before sample collection as it can temporarily affect some blood markers. Schedule your test before starting B12 therapy, blood transfusions, or other treatments that might influence results.
How often should I get tested?
- Initial diagnosis workup: Once, then as symptoms change
- Treatment monitoring: Every 3–6 months
- Stable, managed symptoms: Annually
- New or worsening symptoms: As needed
- Medication adjustments: 2–3 months after changes
Why early detection matters
Early fibromyalgia diagnosis and intervention can significantly reduce healthcare visits, out-of-pocket costs, and improve quality of life (Mayo Clinic 2025). Prompt identification allows for earlier implementation of effective treatment strategies including medication, lifestyle modifications, and supportive therapies.
Without proper diagnosis, patients often undergo unnecessary tests and treatments, leading to increased healthcare costs and delayed symptom management. Early detection also helps prevent the development of secondary conditions like depression and anxiety that commonly accompany chronic pain.
Related tests you may consider
Comprehensive Metabolic Panel (CMP-14) with eGFR Blood Test - Evaluates nutrient levels, liver, and kidney function.
Thyroid #2 Essential Blood Test Panel plus Reverse T3- Provides a detailed evaluation of thyroid function for individuals showcasing signs of thyroid disorder.
Cyclic Citrullinated Peptide (CCP) Antibody Blood Test, IgG - Detects and measures CCP antibodies in the blood to screen for rheumatoid arthritis.
Vitamins Blood Test Panel - Checks for important vitamin levels to help detect deficiencies early, guide treatment, and support your overall health.
