Quick Facts
- Sample: Blood + Urine
- Fasting: Fasting for 14-16 hours is required. Stop biotin at least 72 hours before collection.
- Turnaround: 2-4 business days. May take longer based on weather, holiday, or lab delays.
What This Panel Evaluates
This panel combines blood and urine testing to look at several different aspects of glucose metabolism and related health. Blood glucose reflects your current blood sugar, while Hemoglobin A1c reflects average glucose over the past two to three months. Fasting insulin measures insulin concentration, and C-peptide may show how much insulin your pancreas is making.
Alongside these, the panel includes a Comprehensive Metabolic Panel (CMP-14) with kidney, liver, and electrolyte markers, a Complete Blood Count (CBC), a complete urinalysis, and a urine microalbumin/creatinine ratio. These components provide complementary information, but each measures something different, and no single result confirms or rules out diabetes.
What's Included in This Panel
Comprehensive Metabolic Panel (CMP-14) with eGFR Blood Test
Glucose
Kidney Profile
- BUN (Blood Urea Nitrogen): A waste product formed when the body breaks down protein, normally removed by the kidneys.
- Creatinine, Serum: A waste product from normal muscle activity that is filtered from the blood by the kidneys.
- BUN/Creatinine Ratio: A calculated value (BUN divided by creatinine) that can suggest conditions like dehydration or intestinal bleeding.
- Estimated Glomerular Filtration Rate (eGFR): A calculated estimate of how effectively the kidneys filter waste from the blood, used to assess kidney function.
Liver Panel
- Protein, Total: The combined amount of albumin and globulin proteins in the blood, which helps assess liver and kidney function and nutritional health.
- Albumin, Serum: A protein produced by the liver that helps maintain fluid balance and transport substances through the blood.
- Globulin, Total: A group of blood proteins involved in immune defense, transporting substances, and other important body functions.
- Albumin/Globulin Ratio: A calculated value (albumin divided by globulin) that, alongside other results, can assist in evaluating liver problems.
- Bilirubin, Total: A yellow pigment produced during the normal breakdown of red blood cells and processed by the liver. Elevated levels can cause jaundice.
- Alkaline Phosphatase: An enzyme found primarily in the liver, bile ducts, and bones that can help identify liver or bone disorders.
- Aspartate Aminotransferase (AST or SGOT): An enzyme found in the liver and other tissues, such as the heart and muscles, that is released into the blood when cells are damaged.
- Alanine Aminotransferase (ALT or SGPT): An enzyme that helps identify liver damage. Abnormal levels may represent liver disease.
Fluids & Electrolytes
- Sodium: One of the major salts in your body fluid, important for water balance and the electrical activity of nerves and muscles.
- Potassium: Helps control the function of your nerves and muscles.
- Chloride: Similar to sodium, it helps maintain your body's electrolyte balance.
- Carbon Dioxide, Total: A measure that primarily reflects bicarbonate in the blood, helping assess the body's acid-base balance.
- Calcium: A mineral essential for developing and maintaining healthy bones and teeth, and for normal muscle, nerve, and blood clotting function.
Complete Blood Count (CBC) with Differential and Platelets Blood Test
White Blood Cells
Red Blood Cells and Red Cell Indices
- Red Blood Cells (RBC): Carries oxygen and carbon dioxide to and from your cells. Iron deficiency can lower this count.
- Hemoglobin: A compound inside red cells that carries oxygen through your bloodstream and gives blood its red color.
- Hematocrit: The percentage of blood volume made up of red blood cells.
- MCH (Mean Corpuscular Hemoglobin): The average hemoglobin amount within a single red blood cell.
- MCHC (Mean Corpuscular Hemoglobin Concentration): The average hemoglobin concentration percentage within a red blood cell.
- MCV (Mean Corpuscular Volume): The average size of your red blood cells.
- RDW (Red Cell Distribution Width): Measures the variation in volume and size among your red blood cells.
Platelets
- Platelet Count: Blood cell particles that play a role in forming blood clots.
- MPV (Mean Platelet Volume): The average size of platelets in the blood, providing information about platelet production and activity.
White Blood Cell Differential
- Neutrophils: The most common white blood cell type, created by your bone marrow to combat inflammatory and infectious conditions.
- Lymphocytes: B cells and T cells that fight bacteria and other pathogens, found mainly in your lymph system.
- Monocytes: Work alongside neutrophils to fight infections and clear away dead or damaged cells.
- Eos (Eosinophils): White blood cells that become active in response to allergies and certain infections.
- Basophils: Help detect infections early, support wound healing, and respond to allergic reactions.
- Immature Granulocytes: A component of your white blood cell differential included in this panel. (Labcorp only)
Hemoglobin A1c
Fasting Insulin
C-Peptide
Urinalysis, Complete with a Microscopic Examination
- Specific Gravity: The concentration of the urine sample. This is used to help evaluate the level of certain substances dissolved in the urine. Low specific gravity can result from ingesting large amounts of water before urination.
- pH: This is affected by the acid/base balance in the body. A pH that is too high or low can form crystals in the urine, leading to the development of kidney stones. PH can be adjusted through diet or medication.
- Color: Darker urine coloration can result from some medications, eating certain foods, blood in the urine, dehydration, or fever
- Appearance: Bacteria, red blood cells, white blood cells, mucus, or contaminants such as lotions or powders may cause cloudy or turbid urine.
- WBC Esterase: White blood cells in the urine typically indicate a bacterial urinary tract infection. It may also be caused by inflammation in the kidneys.
- Protein: The amount of albumin in the urine. Protein in the urine can indicate kidney disease or conditions affecting the urinary tract.
- Glucose: Glucose in the urine can be a sign of abnormally high blood sugar levels, such as those caused by diabetes.
- Ketones: Ketones are produced when the body metabolizes fat. They can indicate several conditions, including starvation, a high protein/low carbohydrate diet, diabetes, or frequent vomiting.
- Occult Blood: Blood in the urine can indicate several conditions affecting the kidneys or urinary tract. It can also be caused by contamination from sources such as menstruation, hemorrhoids, or vaginal bleeding.
- Bilirubin: Bilirubin is a waste product produced by the liver. Bilirubin in urine can be an early indicator of liver disease.
- Urobilinogen: Urobilinogen is formed from Bilirubin. Its presence in urine is typically a sign of liver disease. (LabCorp Only)
- Nitrite: Nitrite in the urine is usually caused by bacteria, which can indicate a urinary tract infection.
- Microscopic Examination
- A microscopic examination will automatically be performed if any abnormalities are detected in the initial urinalysis. The microscopic examination may include some or all of the following if the results warrant:
- White Blood Cells (WBCs): WBCs in urine usually indicate inflammation or infection of the urinary tract.
- Red Blood Cells (RBC): RBCs in urine can be caused by inflammation or injury to the kidneys or urinary tract.
- Epithelial Cells: High concentrations of epithelial cells are typically caused by infection or inflammation of the urinary tract.
- Crystals: Crystals may be formed by various particles dissolved in urine. Crystal formation may be due to an abnormal pH balance or a higher-than-normal concentration of particles. Crystals formed in the kidneys may lead to the development of kidney stones.
- Casts: Casts are cylindrical particles formed from proteins secreted by the kidneys. In people with kidney disease, substances such as RBCs or WBCs may become trapped in the proteins. Examining the casts can help differentiate between types of kidney disorders.
- Mucus: Mucus in the urine may result from a urinary tract infection or conditions affecting the digestive system, specific STDs, or kidney disease.
- Bacteria: Bacteria in the urine usually indicate a urinary tract infection. Care should be taken to avoid contaminating the specimen with bacteria from the genital area or hands.
Microalbumin/Creatinine Ratio, Urine
- Albumin, Urine: Measures small amounts of albumin released into urine.
- Creatinine, Urine: Corrects for urine concentration in random (spot) samples.
- Albumin/Creatinine Ratio: Compares urine albumin to urine creatinine.
Uric Acid
Biomarkers tested may vary slightly between labs.
Benefits
- Combines current blood glucose with a two- to three-month glycemic average.
- Includes fasting insulin and C-peptide for added insulin-related information.
- Reports kidney function markers alongside a urine microalbumin/creatinine ratio.
- Adds liver, electrolyte, and CBC results for broader context.
- Brings glucose, insulin-related, kidney, and urine testing together in one panel.
Who Is This Panel For?
- You want current glucose and Hemoglobin A1c results in one panel.
- You'd like fasting insulin and C-peptide results alongside your glucose measures.
- You want kidney-related blood and urine markers reviewed with your glucose results.
- You want liver, electrolyte, blood count, and urinalysis results included as well.
- You're gathering information to discuss with your healthcare provider.
How It Works
- Order Your Test Online
- Visit a Local Lab
- Get Results Online
FAQ
1. Do I need to fast or prepare for this panel?
Yes. Fasting for 14-16 hours is required. Stop biotin at least 72 hours before collection.
2. How quickly will I get results?
Plan on 2-4 business days. May take longer based on weather, holiday, or lab delays.
3. What can this panel tell me?
Think of this panel as several different views rather than one answer. Blood glucose reflects your current level, Hemoglobin A1c reflects average glucose over the past two to three months, fasting insulin measures insulin concentration, and C-peptide may show how much insulin your pancreas is making. Kidney, liver, electrolyte, blood count, and urine results add context beyond glucose.
4. What factors can affect my results?
Several things can influence what your numbers show. Following the fasting window and stopping biotin as instructed helps ensure your specimens reflect the intended testing conditions. Urine concentration also varies through the day, which is why the microalbumin/creatinine ratio uses creatinine as a corrective factor in random (spot) samples. Because biomarkers and ranges can differ slightly between labs, compare results only against the performing lab's ranges.
5. How do I interpret results across the panel?
Read your results as a set of patterns rather than a single score. Glucose and Hemoglobin A1c capture different time frames, and insulin concentration is not the same as the insulin production that C-peptide may reflect. Urine albumin relative to creatinine addresses kidney-related findings rather than glucose. Markers do not have to move together, and one normal result does not cancel an abnormal one elsewhere. Review the full picture with a qualified healthcare provider.
Disclaimer: Reference ranges may vary by laboratory. Listed ranges are general guidelines and may differ from those used by the performing lab. Always consult your healthcare provider for interpretation.
6. What should I do if one or more results are abnormal?
Start by sharing the complete set of results with a qualified healthcare provider. An abnormal result is best understood alongside the rest of the panel and your clinical context, and it does not by itself point to a specific condition or an automatic need for treatment. Your provider can decide whether any additional evaluation makes sense for you.
Pre-test preparation
Fasting for 14-16 hours is required. Stop biotin at least 72 hours before collection.