Growth Hormone, Five Specimens Blood Test
Growth hormone (hGH) suppression by a glucose load is the classic screening test for acromegaly. In addition, the test may be used to monitor the progress of treatment.
DescriptionGrowth hormone excess is the cause of acromegaly. Single growth hormone measurements are not diagnostic because hGH is secreted episodically and cleared rapidly, with a half-life of about 20 minutes. This secretory pattern produces peaks of hGH in serum measurements. Growth hormone is suppressed by glucose in the normal individual. Failure to suppress hGH is diagnostic of acromegaly when coupled with elevated IGF1 and clinical signs of excess growth hormone.
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